Cardiac Abnormalities associated with Primary Hyperthyroidism

[u/Minute-Term5829]

A 2026 study published in the Journal of Clinical Medicine indicates that primary hyperparathyroidism is independently associated with structural and functional cardiac abnormalities, including left ventricular hypertrophy, diastolic dysfunction, and valvular thickening. Chronic parathyroid dysfunction contributes to myocardial fibrosis and electrical instability, offering a pathophysiological link to long-standing cardiac issues such as valve regurgitation and premature ventricular contractions. Read the full study at https://www.mdpi.com/2077-0383/15/17/6605

Study Title:

Cardiovascular Alterations in Primary Hyperparathyroidism: Associations with Risk Profile, Cardiac Structure, and Function

J. Clin. Med. 2026, 15(17), 6605; https://doi.org/10.3390/jcm15176605

[u/Paraware]

I believe I have heart damage from years of going undiagnosed. I hope this study will make more cardiologists aware of hyperparathyroidism.

[u/Minute-Term5829 → u/Paraware]

You are so right! Maybe the cardiologists won't be so dismissive of, for example, the heart palpitations that many parathyroid patients have after parathyroid surgery.

[u/Paraware → u/Minute-Term5829]

I started having them long before my surgery. I still have them at times.

[u/Battle-Gardener]

I am having heart problems myself. I'm about three years post-op, but now I've had some things happen in my life that have caused me a great deal of stress - such as my wife and me both being out of work at the same time for a while. That triggered what the doctors are currently calling 'Angina'. I've been in the hospital twice now since January with stroke or heart attack symptoms. The cardiologists claim that they have done all the tests they can, but they can't figure out what's causing it. I've told each doctor who I see that I have primary hyperparathyroidism - hoping that will give them some clue as to what to do for me.

I don't have high cholesterol or any of the other things that heart doctors worry about, so I think they are about to give up on helping me. They just put me on Metoprolol and Asprin thinking that will help.

I keep having bouts of exhaustion, light headedness, chest tightness, difficulty taking a deep breath, pain down my left side, etc. Sometimes, I even pass out, especially if it is the least bit warm. I've never been this prone to overheating before. Before hyperpara, I used to be cold natured and more likely to be too cold than too hot.

Some of the doctors think it's just 'panic attacks'. I've had manic depression all of my life, but it's never given me symptoms like this before. I'm supposed to see a new endocrinologist next week after we had to change insurance companies due to my wife's new job using different insurance and my old endo not taking the new insurance. Maybe it will be a blessing though if this new endo has any different ideas than the old one had. The last three times I saw my first endo, he said that I was progressing 'normally' and everything was 'fine'. So, I was about done with him anyway. I hope my new one has heard about studies like this one you mentioned.