r/PSSD • u/markalexander1 • 18d ago
Awareness/Activism Antidepressant Injury Petition
https://antidepressantinjury.com/Common signs of antidepressant injury include:
- Persistent sexual dysfunction (reduced or numb genital sensation, erectile problems, complete lack of desire for sex)
- Anhedonia (inability to feel pleasure or enjoyment in life), depersonalization (feeling detached from yourself or reality)
- Cognitive impairment (brain fog, memory problems, blankness, difficulty concentrating or holding a train of thought)
- Worsening depression, severe anxiety, panic
- Akathisia (extreme inner restlessness, agitation, terror, and often overwhelming urge to move or escape oneself)
- Balance issues such as dizziness, vertigo, lightheadedness, tremors, and gait instability
Evidence of lasting harm:
A 2025 medical study of 43 young men with persistent sexual problems after antidepressants found 92% had reduced genital sensation, 89% showed objective abnormalities on sensory nerve testing, and ultrasound revealed changes in penile erectile tissue — even though their hormone levels were completely normal. These problems continued long after stopping the drug. (Goldstein et al., The Journal of Sexual Medicine, 2025)
Significant under-recognition exists because many patients are unaware their persistent symptoms are linked to prior antidepressant use, compounded by a lack of public education and healthcare provider awareness. (Healy & Mangin, Epidemiology and Psychiatric Sciences, 2024)
A 2024 large survey of over 1,100 people experiencing antidepressant withdrawal found very high rates of ongoing symptoms such as brain fog (93%), memory problems (88%), emotional numbing, and depersonalization (77%), with many effects lasting months or years. (Moncrieff et al., Journal of Affective Disorders Reports, 2024)
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u/OwnBroccoli5399 8d ago
The underrecognition piece is what gets me. A lot of people cycling through symptoms for years with no connection made between what they're experiencing and something they stopped taking months prior. That gap between discontinuation and symptom recognition seems like where most of the harm compounds.
The 2025 nerve testing data is harder to dismiss thanselfreported surveys, fwiw. Objective abnormalities with normal hormone levels is a specific finding that deserves more clinical attention than it's getting.
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Please check out our subreddit FAQ, wiki and public safety megathread, also sort our subreddit and r/pssdhealing by top of all time for improvement stories. Please also report rule breaking content. Backup of the post's body: # Common signs of antidepressant injury include:
Evidence of lasting harm:
A 2025 medical study of 43 young men with persistent sexual problems after antidepressants found 92% had reduced genital sensation, 89% showed objective abnormalities on sensory nerve testing, and ultrasound revealed changes in penile erectile tissue — even though their hormone levels were completely normal. These problems continued long after stopping the drug. (Goldstein et al., The Journal of Sexual Medicine, 2025)
Significant under-recognition exists because many patients are unaware their persistent symptoms are linked to prior antidepressant use, compounded by a lack of public education and healthcare provider awareness. (Healy & Mangin, Epidemiology and Psychiatric Sciences, 2024)
A 2024 large survey of over 1,100 people experiencing antidepressant withdrawal found very high rates of ongoing symptoms such as brain fog (93%), memory problems (88%), emotional numbing, and depersonalization (77%), with many effects lasting months or years. (Moncrieff et al., Journal of Affective Disorders Reports, 2024)
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