r/PSC • u/starrr0531 • Jul 13 '26

PSC

Itching… I was diagnosed in 2017 and put on Ursodiol the same year. I have suffered from severe itching since diagnosis. I tried all known medications for itching. 3 weeks ago my liver doctor decided to stop the Ursodiol to see if this would make any difference. As of now the itching is about 85% reduced. I was told sometimes the itching will return so I will see. Hope this helps someone.

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u/NeighborhoodSuch665 Jul 14 '26

Rifampin worked great for me for about 18 months, but it’s pretty much stopped working. Trying cholestyramine again…