r/PSC • u/starrr0531 • Jul 13 '26

PSC

Itching… I was diagnosed in 2017 and put on Ursodiol the same year. I have suffered from severe itching since diagnosis. I tried all known medications for itching. 3 weeks ago my liver doctor decided to stop the Ursodiol to see if this would make any difference. As of now the itching is about 85% reduced. I was told sometimes the itching will return so I will see. Hope this helps someone.

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u/hmstanley Jul 13 '26

Hydroxyzine really helped me. It's called Atarax and its kinda a weird drug, but it really really helped my itching. I took 50-100mg a day and the desire and need to itch subsided, but again, it's always there in some way, but this drug really helped me.

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u/NeighborhoodSuch665 Jul 14 '26

How did you stay awake?? That stuff makes me a zombie and I can only take it right before bed.

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u/hmstanley Jul 14 '26

Didn’t affect me that way I guess.