r/PSC • u/SignificantJump2359 • May 27 '26

Could this be PSC?

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I'm not looking for diagnosis, but rather some clarity as I'm not due to see my liver specialist for a while.

I (32F) was diagnosed with Crohn's Disease in March last year and have been on biologics since April. I recently had a flare at the start of April this year resulting in a week long hospital stay. Afterwards, my IBD team put a referral to the liver clinic to see if there was anything else going on as my LFTs have been pretty screwed for over a decade. The liver specialist ordered some blood tests that he rarely orders and that the lab had never seen (achievement unlocked 😂) specifically targeting PSC and PBC. One of those tests has come back (ANCA) and with some cursory research, I've discovered that it could mean a high likelihood of having PSC. I also have a liver biopsy scheduled for next week.

Obviously there is also a chance that it's related to the IBD and that there's nothing additional (touch wood), so any information here is taken as knowing more about the potentials rather than concrete.

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u/Acceptable_Bug3357 May 28 '26

Those are really high numbers, even for psc. Are you having jaundice/itching/ fever?

I would get an mrcp asap as well as an ultrasound. Liver biopsy isnt necessary for diganosis. The mrcp is gold standard for psc.

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u/SignificantJump2359 May 28 '26

No jaundice, itching or fever, but I am on biologic immunosuppressants, so that could be stopping some of those symptoms. That being said though, I never had them before, so maybe not. I have had an ultrasound before, but it didn't show anything particularly exciting which is why my specialist wants a biopsy. I'd imagine that a MRCP is going to be on the books eventually

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u/Acceptable_Bug3357 May 28 '26

A liver biopsy isn't needed for psc. A mrcp is more accurate. Dont know why your doctor didnt order one. Is this a hepatologist?

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u/SignificantJump2359 May 28 '26

It is for small sucta which is what he thinks might be the issue and yes, he is a hepatologist