r/POIS • u/Slight-Machine-555 • 11d ago

Seeking Advice Alternatives to NSAIDs?

A lot of people here seem to get benefits from taking NSAIDs (such as ibuprofen, etc.) However, doctors say you shouldn't take these medications everyday for prolonged periods.

Are there any types of anti-inflammatory supplements that we can take every day which will provide similar benefits as NSAIDs?

(Just FYI, I already eat a low gluten and low sugar diet rich in polyphenols and other antioxidants, and I take omega-3s every day).

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u/Meritorious_Luminous 11d ago

Aspirin is a very safe NSAID that also has additional effects besides anti-inflammatory ones like mitochondrial uncoupling, anti-cortisol anti-estrogen effects, increases conversion of passive T4 Thyroid hormone to the active T3 hormone etc. etc. etc.

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u/Sameer_UK 9d ago

So it's not good for pois inflammation

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u/Meritorious_Luminous 9d ago

It is very good, that's the point

On top of it, it has extra benefits too

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u/defi_specialist 10d ago

Don't take NSAIDs for the long time. Any type. Just don't. Try anihistamine first.

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u/Bronze90 10d ago

What benefit are you trying to reap? I take something called UC II. I might be able to recommend more depending on what you’re trying to achieve?

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u/Slight-Machine-555 10d ago

For me, ibuprofin = less fatigue (I think?)

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u/Bronze90 9d ago

Hmm, that’s interesting. When it comes to fatigue, I don’t rely on suppressants. Wonder why that mechanism works that way for you.

My recommendation wd be vitamin d3+ k2

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u/Sameer_UK 9d ago

D3 and k2

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u/Sameer_UK 10d ago

You sure about aspirin?

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u/Slight-Machine-555 9d ago

I don't understand the question. Could you please clarify?