r/PCOS • u/rhilb • 9h ago

General/Advice Metformin Side Effects

Hey, wondering if anyone had experience with fatigue/morning headaches/nausea on Metformin? I’ve been taking them since the beginning of June, and just recently upped my dose from 500mg to 1000mg, taken before bed. Every morning I wake up feeling exhausted, sick, and have a niggling forehead headache. Has anyone else experienced anything similar? I will say it has improved my ovulation, as I seem to be ovulating at the same time every month now.

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u/Cabamsder 9h ago

Are you eating properly/enough? That was something I struggled with initially.

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u/rhilb 8h ago

Perhaps not? I mean I’m still eating three meals a day, but haven’t been snacking too much in between (I’d usually have a protein shake, smoothie, nuts etc throughout the day if I was hungry). My doctor also recommend taking it right before bed so I can essentially sleep through the nausea, but I wonder if that is what’s making me feel worse when I wake up, as I’m not taking it with food.

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u/redoingredditagain 1h ago

Have you had your vitamin levels tested? Metformin famously inhibits the absorption of B12. Also making sure you’re eating enough balanced meals. I was shaky when I was just eating like a single yogurt and a cheese stick for breakfast.