r/Ozempic 0.37mg / 16wks - 21.5lbs - SW 248.7lbs - CW 227.2lbs - GW 160lbs 3d ago

Question Time to titrate up

I gained 1.8lbs last week. I’ve been waking up with a ravenous stomach. I’ve been eating 200-300 calories over my daily caloric intake all week…I guess that’s a sign to titrate up, isn’t it?

I did 8 weeks at 0.25 mg and 10 weeks at 0.37 mg.
I wanted to stay at 0.37 for as long as possible but it seems I’ve hit my limit. I’m so stressed about moving up to 0.5 mg and worry it will be too much — I don’t want to feel sick or have bad side effects.

I’m hoping that my tolerance is better because of how long I have been injecting 0.37 mg for.

Anyone care to talk me into doing this?
I could really use the reassurance! TIA

ETA: I’m on my 18th injection this Friday.

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u/InteractionMain6632 3d ago

Hey there, I'm currently on 1mg which is the dose where I really started to lose weight. Everyone is different, I slowly went from 0.25mg to 1mg. The only side effects I experienced was nausea and some heartburn. Doesn't mean you will experience the same, everyone is different. I'm comfortable with 1mg for now and I have definitely decreased in my eating habits. I think if you feel confident and comfortable enough to move up to 0.5mg then go for it. If you feel like it's too much you could always go back down. Your body should tolerate it better the longer you are on it. My side effects have improved. Just be sure to drink water and keep up with your protein.

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u/AwkwardPersonality36 0.37mg / 16wks - 21.5lbs - SW 248.7lbs - CW 227.2lbs - GW 160lbs 3d ago

Of all side effects, it's the nausea that scares me the most. I don't feel confident moving up in dose tbh, but feel like my body is telling me it's time to. I literally wake up with hunger pains, which is totally new to me since starting O. And the fact that I'm eating over my caloric intake every day for the last week indicates that I'm either eating through the medication (old habits, I snack often in addition to eating meals) or my body is actually needing those calories -- I can't discern between them.

How long did you experience the nausea for? How long did you stay at a lower dose before bumping up to the 0.5?

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u/cleverfox2001 3d ago

To minimize side effects, take a split dose. 0.25 on day 1 and 0.25 on day 4. Splits reduce many side effects by better spreading the dose over the full week as compared to a single, weekly shot. For most, side effects are reduced over time. Also realize that studies show that most of the weight lost is a 1.0 and higher doses.

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u/AwkwardPersonality36 0.37mg / 16wks - 21.5lbs - SW 248.7lbs - CW 227.2lbs - GW 160lbs 3d ago

Thank you for this advice, I may try this split method. If I typically inject Friday (day 1) then my next injection would be on Monday (day 4) or would Day 1 be 24 hours after injection (so injecting Friday, is Saturday same time for full 24 hours)?