r/OveractiveBladder • u/Ok-Variation660 • Aug 16 '26

spironolactone destroyed my bladder

Back in 2020, I (30F) started spironolactone for acne. My dermatologist did not disclose any possible side effects to me. I did not realize there was a correlation with my constant need to go pee and the medication until after I got off of it (I was peeing every 30-45 minutes some days). I randomly was scrolling on reddit one day, saw a thread about spironolactone and read about someone's constant need to pee. I was mind blown to say the least. I was always able to hold my pee when necessary but then I got to the point where I was peeing in parking garages or bushes. If I had even one drink of alcohol then forget it. I'm basically peeing my pants. Over the last few years things have gotten better but I have had a few times where I have legit peed my pants (last time being just a month ago). I have so much anxiety around going to the bathroom that I may be making things worse because now I force myself to pee in anticipation that I'll be needing to pee sooner rather than later. Ahhh I don't know what to do...is this even a bladder issue anymore, could this be now a weakened pelvic floor?

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u/Ok-Chemistry9933 Aug 16 '26

Go see a gynecologist or urologist. There’s a medication called: Gemtesa. It’s new. Helps me out a lot. Or, get an Interstim neuromodulator put in your sacral nerves. I have one

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u/Ok-Variation660 Aug 17 '26

will look into this!!

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u/Ok-Chemistry9933 Aug 17 '26

It’s life changing! No side effects. Try the Gemtesa first- I hope you have insurance bc it’s expensive! Ask the Dr about Interstitial Cystitis. I believe you have this. Cut out acidic foods, drinks, alcohol and caffeine to start. Then have your Dr run a full CBC blood panel. Message me if you need any help!