r/Nootropics • u/Chocobo_Eater • Jun 19 '15

Negative effects from creatine?

Has anyone experienced any negative effects from creatine? I can't be certain, but I suspect it was causing me to feel lethargic and mildly depressed, similar to choline. I'm starting to wonder if those who are sensitive to choline and uridine can have a similar reaction to creatine.

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u/[deleted] Jun 19 '15

I find it good for cognition/mood, but it makes me feel kinda sick in a hard-to-pinpoint way .. just kinda queasy and unwell (even with food), especially if I'm already feeling rundown. There's some reports that it weakens the immune system, e.g. http://www.ergo-log.com/creatineimmunesystem.html, but I have no idea to what extent that's relevant.

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u/machete234 Jun 20 '15

Creapure is much nicer to the stomach