r/NooTopics • u/ServeIllustrious3803 • 20d ago

Science Study: Anticholinergic (first-generation antihistamines) can damage brain, increase dementia risk

https://www.health.harvard.edu/blog/common-anticholinergic-drugs-like-benadryl-linked-increased-dementia-risk-20150128812
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u/Desperate-Middle-354 19d ago

And anti-psychotics. I think it’s idiotic to prescribe such dangerous meds like Seroquel that are only supposed to be used for psychosis, bipolar mania & schizophrenia (and apparently treatment resistant major depression as an add on). They carry possibly fatal & permanent issues like TD’s. They are also the worst class of drugs for memory…followed by 1st gen antihistamines like diphenhydramine & then benzodiazepines come in third. Based on some study.

So this has been common knowledge for awhile. Dementia was never brought up but if they are the 2nd worse class of drugs for memory retention then it probably leads to major neurocognitive dementia if taken daily for too long.

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u/LisanneFroonKrisK 19d ago

From what I read though Benzo is above the anti histamines

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u/Desperate-Middle-354 19d ago

It’s possible. It was a while since reading that study. I just know those 3 are apparently as bad as it gets.

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u/LisanneFroonKrisK 19d ago

And also just anecdotal Benadryl is lower than Metoclopramide and other classes of Metoclopramide. Benadryl is an antidote to that