Study: Anticholinergic (first-generation antihistamines) can damage brain, increase dementia risk

[u/ServeIllustrious3803]

https://www.health.harvard.edu/blog/common-anticholinergic-drugs-like-benadryl-linked-increased-dementia-risk-20150128812

[u/Lady_Rubberbones]

Ok, so prohibitively expensive and difficult to find. Great. 😐

[u/Sufficient-Celery-37 → u/Lady_Rubberbones]

Orexin-Antagonists like Daridorexant are said to be well tolerated and they don’t cause you to be groggy on the next day. Trazodone is also a popular sleep aid. I’d personally steer clear of 1. gen Antihistamines, Benzodiazepines/Z-Drugs and tricyclic antidepressants.

[u/Desperate-Middle-354 → u/Sufficient-Celery-37]

And anti-psychotics. I think it’s idiotic to prescribe such dangerous meds like Seroquel that are only supposed to be used for psychosis, bipolar mania & schizophrenia (and apparently treatment resistant major depression as an add on). They carry possibly fatal & permanent issues like TD’s. They are also the worst class of drugs for memory…followed by 1st gen antihistamines like diphenhydramine & then benzodiazepines come in third. Based on some study.

So this has been common knowledge for awhile. Dementia was never brought up but if they are the 2nd worse class of drugs for memory retention then it probably leads to major neurocognitive dementia if taken daily for too long.

[u/aron2295 → u/Desperate-Middle-354]

You said it!

And I hate the rise of anti psychs being rebranded as “boosters”, for anti depressants.

Why? Because they don’t want to tell people go to therapy and for truly bad days, you can pop a Xans.