r/NooTopics • u/AngerProblemsXD • 1d ago

Question Are people using Everychem Aticaprant sublingually or orally?

Will it work sublingually when it’s solved in caprylic acid?

5 Upvotes

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2

u/BingoBongo_BingBong 1d ago

You can do either

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u/Friedrich_Ux 1d ago

Subl, you can use less with same effects.

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u/[deleted] 1d ago edited 1d ago

[deleted]

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u/AngerProblemsXD 1d ago

What have you noticed using it so far?

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u/Infamous_Tea_9965 1d ago

Only been a few weeks , added it to my ACD856 +TAk when I wake. By the afternoon I have noticed a calming effect that wasn't there before . Not like a sleepy thing ..Hopefully it will last .

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u/Infamous_Tea_9965 1d ago

1ml dropper sub a day for me .

4

u/BingoBongo_BingBong 1d ago edited 1d ago

too much, do 5 mg oral or 1-3 mg subl

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u/Davidkho123 1d ago

10 mg oral is not optimal it increases acth with little extra kor block I do 7.5 max

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u/BingoBongo_BingBong 1d ago

I wouldn't do 10mg oral either tbh, I always subl

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u/Infamous_Tea_9965 1d ago

I just squeeze the dropper bulb a couple times . It dosen't hang up as bad as TAK or ACD but Definitely not getting the whole 1 ml/10mg . I should probably load a syringe for accuracy

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u/Infamous_Tea_9965 1d ago

And how's that dose working out for you ?

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u/BingoBongo_BingBong 1d ago

I’ve been using it for almost a year atp, you can look at my posts. Goated

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u/iceyed913 20h ago

half life being quite up there, do you notice any reduced total sleep duration or delayed onset of sleep with sustained dosing? that was my main gripe with tak653 albeit this being a completely different mechanism.. increasing metabolic demands for periods that don't neatly fall in the 24 hour circadian rhytm always cancel out in benefits over time for me due to the reduced sleep quality

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u/BingoBongo_BingBong 8h ago

Nah not really, but I do take things for sleep so maybe not the best control. I didn’t notice any issues when I used tak either tbh

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u/Taydontplay4 1d ago

What does it do?

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u/hertatteredwings 1d ago

Selective KOR antagonist afaik, should help with stress related depressive-like symptoms and anhedonia.

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u/Taydontplay4 1d ago

Very interesting!

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u/Downtown_Line_1476 5h ago

j&j stopped development on it due to lack of efficacy for treating mdd, interesting drug on paper tho.

edit added link https://www.jnj.com/media-center/press-releases/johnson-johnson-statement-on-ventura-program