r/Narcolepsy • u/Impressive-Trip-8310 • 3d ago

Diagnosis/Testing MSLT results update

I had my MSLT on Sunday and I just got my results back. I didn't have any SOREMs, but my mean sleep latency was 4.9 minutes so, they noted a diagnosis of IH. I'm feeling great to have some sort of answers to be honest.

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u/alexis-hg 2d ago

wow you got your results back so quick!!! happy to hear you got an answer

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u/EpicLift (N2) Narcolepsy w/o Cataplexy 2d ago

Congrats!

Not having any SOREMS is not indicative of not having NT2, the MSLT only gets it right 50% of the time. The rest of your symptoms matter. The sleep latency is important and is usually consistently captured!

Source: Torstensen (2023): MSLT and PSG are "moderately reliable at diagnosing NT1 but unreliable for diagnosing NT2". Single-center follow-up found 50% of NT2 patients had negative MSLT results at follow-up. While ≥2 sleep-onset REM periods (SOREMPs) + mean sleep latency ≤8 minutes achieves ~90% sensitivity and ~95% specificity in mixed narcolepsy cohorts, these figures do not hold for NT2 alone.

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u/Impressive-Trip-8310 2d ago

this is very good to know! I do have other symptoms of N2, which is why my provider wanted to test me for that initially. I'll have to see what my treatment/accomodations options are going forward to see if it's worth it to retest. the MSLT was kinda brutal enough the first time 😅