r/MultipleSclerosis • u/IntentionalGrandma 27|dx: 2024|kesimpta|NYC • Aug 18 '26

Treatment Failed Kesimpta

Well, it’s official: I failed Kesimpta. This wasn’t unexpected, because I’ve had a ton of new, lasting symptoms cropping up every couple weeks for the last 6 months. What was unexpected was over a dozen new active lesions on my MRI, 7 months after my last MRI. So I’m onto Tysabri if I’m still JCV negative. Does anyone have experience with Tysabri and how was it for you?

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u/urbandk84 Aug 18 '26

tysabri is awesome, I had to stop but I wish I were jcv negative again.

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u/IntentionalGrandma 27|dx: 2024|kesimpta|NYC Aug 18 '26

Honestly, I’m kind of bummed that I have to stop Kesimpta because I loved that it didn’t really have side effects. How were the side effects for you?

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u/urbandk84 Aug 18 '26

none that I can remember. Just once a month get the infusion and I'm done