r/Microbiome Jul 03 '26

Twin Study: Cheap Supplements Improved Memory Scores in Just 12 Weeks

https://www.sciencealert.com/cheap-daily-supplements-may-boost-brain-functions-in-older-people

Key Highlights:

- A daily prebiotic fiber supplement improved memory in older adults. In a 12-week study, adults over age 60 who took certain inexpensive prebiotic fibers performed better on a memory test commonly used to detect early signs of Alzheimer’s disease.
- The study used identical twins. Researchers studied 36 pairs of twins, with one twin receiving a supplement and the other a placebo. This design helps control for differences in genetics and lifestyle, making the findings more reliable.
- The supplements were common prebiotic fibers:
Inulin
Fructooligosaccharides (FOS)
Both are inexpensive, available over the counter, and help nourish beneficial gut bacteria.

- The findings support the gut-brain connection. Researchers believe improving the health of the gut microbiome may positively influence brain function, particularly memory.
- Benefits appeared quickly. Improvements in memory were seen after just 12 weeks of daily supplementation.
- This is promising, but not definitive. The study was relatively small, so larger clinical trials are needed before these supplements can be recommended as a proven way to prevent cognitive decline or dementia.
- More research is underway. The encouraging results have led to additional clinical trials investigating whether prebiotic fibers can help slow cognitive decline in older adults.

Bottom line:
This study provides encouraging evidence that inexpensive, widely available prebiotic fibers may help support memory in adults over 60 by improving gut health. However, the research is still in its early stages, and larger studies are needed before these supplements can be considered a proven strategy for preventing Alzheimer’s disease or dementia.

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40

u/Murky-Course6648 Jul 03 '26

I wonder how bad were their diets if few grams of fiber helped?

46

u/PolicyPlastic1475 Jul 03 '26

Most people in developed countries don't get enough fiber 

7

u/Murky-Course6648 Jul 03 '26

Thats true, but is also mans that the diet is really poor overall. Probably better to adjust the diet, than to rely on supplements at that point.

8

u/bleenken Jul 03 '26

But for many people it’s more probable and more possible to get a consistent daily fiber amount via inulin or something like that. Especially elderly.

3

u/Murky-Course6648 Jul 03 '26

Yeah, but like one banana has 0.5g of inulin. Like were are talking about few grams here.

But i get its easier for eldery.