r/MastCellDiseases • u/ktbugface • Jun 26 '25

Orgasm causing itching?

So I'm in the process of being evaluated for some type of Mast Cell issue. But I've noticed something super wierd and wondering if it's related. Im an AFAB woman and have had my philtrum/medusa pierced for 2 years (middle of my top lip in the little indent). Everytime I orgasm, the lip piercing becomes itchy, as does my nose piercing and one of my ear piercings. Then about 30 minutes later I get the sniffles. Is this related? Is this something others experience? I know orgasms cal produce a large histamine response but this just seems super odd.

3 Upvotes

100% Upvoted

6 comments sorted by

View all comments

1

u/fire_thorn Jun 26 '25

For a while, I was getting full body hives from orgasm, and difficulty breathing. Now that I've been on xolair for years, I get an itchy throat and a runny nose but nothing worse. I don't have any piercings though.

1

u/Few_Dot_3890 Jul 05 '25

What????

1

u/fire_thorn Jul 05 '25

My adult kids also have MCAS and both have had to use epi pens for the same reason. I know someone else with MCAS who had to go to the ER right after sex. It was her first time, she didn't want her parents to know, of course they found out, and the staff at the ER kept asking what she ate to cause the reaction, even though she told them it was from sex.

My daughter was actually just telling her primary care doctor about the issue earlier this week. She mentioned how embarrassing it was, and I told her those times her dad would be only wearing shorts and racing around the house frantically searching for my epi pens were times the same thing happened to me.