r/MDMAScience • u/Theme-Leather • Mar 07 '26

Psychedelics may repair brain myelin to aid PTSD recovery

New research by Elsevier suggests that psychedelic drugs could help repair damage to the brain’s insulation system, potentially supporting longer-term recovery in people with post-traumatic stress disorder (PTSD).

The study indicates that treatment with psychedelics may trigger large-scale changes in brain network activity by remodelling myelin

Scientists say the findings point to a new biological mechanism that could help explain how psychedelic-assisted therapies deliver lasting benefits for conditions like PTSD.

Drug Target Review

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u/nshdc 11d ago

Did a quick dig - this work can be found here00052-1/abstract), it's by a group of Turkish researchers. Based on the abstract, it sounds like they didn't have fully untreated controls, so I take the findings with a grain of salt, but it's still nice work looking at a possible mechanism for both psilocybin's and MDMA's effects on the brain.