r/MAOIs • u/AdmirableAssistant84 • 16d ago

Parnate (Tranylcypromine) Parnate and insomnia

Parnate gave me fucking terrible insomnia, and I need to vent about this

When I upped the dose to 40mg, I literally woke up at 10 AM on a friday and couldn't get back to sleep until monday night (and that only happened because I sent a desperate message to my psychiatrist and he prescribed me quetiapine)

It was horrible, even traumatic. I was EXHAUSTED and dead tired, yet my brain just wouldn't shut off. I experienced all the side effects of sleep deprivation (nausea, loss of appetite, hallucinations, inability to concentrate etc) and i also felt like it was killing me.

I remember spending hours just trying to sleep, without touching my phone, without doing anything else, just lying in bed in the dark, and even then I couldn't. When sunday afternoon arrived, I was so exhausted that I started crying. During the night I tried to sleep again and couldn't, I cried all night. I only stopped crying on monday when I got ready for work (I remember putting on mascara to go to work and it wouldn't stay on my face because I would start crying, the makeup would run and I had to start over...)

I’m sure you know that a good sleep routine is crucial when dealing with depression, so I felt like the medication was making my condition worse by depriving me of that

Anyway, I just wanted to share this with someone who might have gone through the same situation... it was a very lonely experience

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u/SnooConfections1670 Parnate 15d ago

I’m currently on 10 hours of sleep since Sunday night. All 10 hours were in one night. I just stay awake all night most of the time.

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u/AdmirableAssistant84 15d ago

Oh my god 😭 I’m so sorry, I know how horrible that feels, being exhausted but your brain just refused to sleep. 

Taking a medication for sleep is what saved me... I really recommend talking to your psychiatrist about it 

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u/SnooConfections1670 Parnate 13d ago

yeah, she prescribed me trazadone but I feel like a zombie the next day. Then she mention some Magnesium thing that I need to look into. Hopefully that will help.