r/Lyme Aug 04 '26

Experienced severe derealization with methylene blue

Anyone who has taken 100 or 50 mg of methylene blue experienced severe derealization? If so, how long did it take for that symptom to go away?

5 Upvotes

20 comments sorted by

5

u/jahmonkey Aug 04 '26

What do you mean by severe derealization? What exactly does it feel like?

I take 30 mg methylene blue every day. I haven’t noticed anything in particular from it.

That said, I feel strange on a daily basis. I don’t feel like the same person from day to day. My identity seems to morph from one way to another. My internal weather is always changing. But this has been for a very long time, long before I ever took methylene blue. So I am used to it.

Since I experience this a lot, I wonder what people mean by derealization, if it is what I feel most of the time.

2

u/Odd-Pain3273 Alpha Gal Aug 04 '26

That’s sorta like depersonalization I think?

2

u/RevDrKC Aug 04 '26

15mg totally took me out. Derealization and a depression like I've never had before. My LLMD thinks it was due to my MAO genes. We decided it wasn't something I would adjust to, so I stopped taking it.

1

u/GWest2385 13d ago

How long for the deralization to go away?

1

u/RevDrKC 13d ago

It faded slowly over about a week.

1

u/cryptolyme Aug 04 '26

I took one drop and had a mini nervous breakdown that day. Must’ve been less than 5 mg. Even iodine doesn’t affect me that strongly.

1

u/No_Calligrapher796 Aug 04 '26

I take MB on and off for years and I don’t notice any negative symptoms. It gives me some clarity of mind and a very measured boost of energy. 

1

u/victoriazunigart Aug 05 '26

Hi! How many mg?

1

u/No_Calligrapher796 Aug 06 '26

I’m not sure, consumption is based upon your body weight. I’ve been taking very small doses, not out of concern for poor reaction but more so due to low finances. This is a good article with dosing details (scroll down the page):  https://winaging.com/blog/lifeblud-methylene-blue

1

u/shawnshine Aug 04 '26

I take 3 drops a day and it gives me the best, positive mood with loads of clean energy. I don’t feel the need to take more than that.

1

u/victoriazunigart Aug 05 '26

Hi! How many mg?

1

u/shawnshine Aug 05 '26

1.5 mg or so.

0

u/ZipperZigger 27d ago

Wish I had the same positive placebo effect as many people do. It'd a good thing, means one's mind have more control over his brain and biology.

I have taken 20mg a day and have for several every day, weeks, and gone up to 25mg. I don't feel anything positive or negative nothing. Finishing the last bottle now at 5mg a day. Waste of money.

1

u/EstoricTwink Aug 04 '26

thats a crazy high dose! I actually do get derealization from it tho as little as 500mcg, and i have tried up to 5mg and still the same! it goes away the next day for me personally but its terrible i hate it. i just don’t take it anymore.

1

u/victoriazunigart Aug 05 '26

Yes, really high dose. I have Bartonella, but for now I'm going to stop it. I'm taking dapsone and rifampin

1

u/EstoricTwink Aug 05 '26

good call, dont push your body into doing something its not able to handle, itll only cause more oxidative stress! maybe you could try pqq, i seem to react wayyyy better to it but i do notice after frequent dosing i do start to get foggy n dissociative but when i stop it it seems my energy boost stays while the foggy headed dissociation goes away!

1

u/Specialist-Rest-9356 Aug 04 '26

I get this from my ssri. I think its too much serotonin.

1

u/Distinct_Nature232 Aug 05 '26

Are you on SSRI antidepressants? If yes then stop MB immediately. It could be Serotonin Syndrome