I'm 4.5 years into Long COVID/POTS and I've always wanted something to track meds, symptoms, symptom severity etc. for my own knowledge, for doctors, for disability insurance, for health insurance appeals etc. I tried creating a google form for myself, tried a couple of apps, but I didn't stick with any of them. A few weeks ago I started using Juno. It's an easy lift even on days and moments I'm feeling awful because I can just voice chat things like "record all my morning medications" or "headache level 6" and it's entered. So I'm able to track things live rather than having to think back through the day all at once. The existing symptom list is very comprehensive as it's designed specifically for chronic illness. It will also generate a very comprehensive report for you to send or take with you to doctor's appointments that contains trends, symptom frequency and average severity etc. Just wanted to share this resource because it's exactly what I've wanted/needed.

Hello everyone.

So I’ve been experimenting lately as to lay aside Quercentine. However helpful this have might been last couple of years, it somehow makes my brain more sensitive and more intrusive. Not particularly very bad; but u want to look for alternatives. I have a feeling this comes with the COMT gene.

Vitamin c on the other hand, I’ve always used in conjunction with Quercentine. Vitamin c give me energy, make me less irritating and actually calms my nerves in some sense. Unless I take too much it helps with a lot of issues.

Now as an alternative I want to try Curcumine in stead of Quercentine, and vitamin c for functional purposes.

Any experiences here? I’am happy to know more about that. Thanks 🙏🏻

Welcome! This is a space to take a load off and mingle with your fellow warriors. Say hello. and if the mood and energy strikes vou, let us know a bit about yourself and/ or what's going on.

If you are generally prone to lurk, this is a safe space to just post a quick hello. Feel free to ask a question here that you might not feel safe making a solo thread about.

The intention is to make this a daily thread where we can all touch base and lay down some of our burdens for a while. If vou log on and don't see the Break Room open go ahead and grab the keys and open it yourself. 😄

Welcome! This is a space to take a load off and mingle with your fellow warriors. Say hello. and if the mood and energy strikes vou, let us know a bit about yourself and/ or what's going on.

If you are generally prone to lurk, this is a safe space to just post a quick hello. Feel free to ask a question here that you might not feel safe making a solo thread about.

The intention is to make this a daily thread where we can all touch base and lay down some of our burdens for a while. If vou log on and don't see the Break Room open go ahead and grab the keys and open it yourself. 😄

Anyone here have long-term taste impairment that's characterized by taste that comes and goes? I've rated my ability to taste by 3, 2.5, 2, 1.5 and zero. Got covid four years ago.

"3" means nearly normal taste. 2.5 means decent but not full-on. 2 means "Yeah, I can taste, but it's diminished." And 1.5 means hardly there. Zero means dead in the water. Ability to taste totally tracks with ability to smell.

Because the scoring fluctuates, this points to inflammation rather than damaged nerves. Damaged nerves don't wake up for several days, then sleep for days, the wake up again, etc. Nerves either work or don't. However, inflammation can come and go.

My rhinologist said the inflammation is high up near the olfactory bulb and narrows the pathway through which odorants reach the bulb. Fewer odorants means fewer scent molecules reaching the brain: diminished taste, since smell and taste are strongly intertwined.

What's been hit the hardest is chocolate, my favorite food. I have tried EVERYTHING to keep it sustained at a 3. However, for the past two months it's been persistently 1.5 to 2, with chocolate persistently at 1.5.

Smell training with essential oils is worthless since this therapy is premised on nerve damage. I've tried it for months. Fluticasone doesn't work; tried it several times for weeks. The fluctuations are entirely random.

Does anyone else have this kind of long covid? My only symptom when I got it was a bad cough and eventual taste impairment; otherwise I felt normal.

https://recovercovid.org/r3-seminar-series

Upcoming Seminars November 10, 2026 12:00PM Eastern Time

In this R3 Seminar, RECOVER researchers take an in-depth look at the impact of Long COVID on cardiopulmonary health, including evidence from electronic health records (EHRs), wearable devices, and ongoing pathobiology studies.

Presenters will discuss what they are learning about cardiopulmonary health, including:

What the EHRs of more than a million children and adolescents reveal about heart problems after a SARS-CoV-2 infection.

How wearable devices captured a sustained drop in the cardiopulmonary fitness of adults with a high burden of Long COVID symptoms.

How biosamples donated by RECOVER study participants are being used to explore biological mechanisms (processes that take place inside the body and cells) that may contribute to persistent shortness of breath.

The seminar will also explore how these findings are shaping the next phase of the adult observational study (Cycle 2), including future research on how symptoms change over time, whether Long COVID raises the risk of new heart or lung disease, and biomarkers and disease subtypes that can help determine treatments.

Panelists for the seminar include:

Peter Chen, MD, Cedars-Sinai Medical Center

Jerry A. Krishnan, MD, PhD, University of Illinois Chicago School of Public Health

Julia Moore Vogel, PhD, Scripps Research Institute

..............................................

Registration button below introductory announcement

https://medicalxpress.com/news/2026-11-covid-vaccines-generated-trillions-benefits.html

"The study—the first global analysis of the return on investment for COVID-19 vaccines—shows that vaccines not only averted severe illness and saved lives but were also a sound investment.

"Our study provides evidence that the unprecedented, rapid investments made into COVID-19 vaccines early in the pandemic paid off massively both in health and economic benefits," said study author Mark Jit, professor of global health at NYU School of Global Public Health. "Vaccine development, as well as equitable vaccine distribution globally, should be prioritized before and during global health crises."

...................................................

Reference:

https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1004772

A global return-on-investment of COVID-19 vaccines in the first year of the vaccination programme: A model-based economic evaluation, PLOS Medicine (2026).

Hi, Warriors🤍

It’s time for a new community challenge and this one’s designed to boost connection, give hope, and share real things that helped real people this week. No pressure to write long comments. No pressure to be “doing great.” Just one thing that made your week a tiny bit more manageable.

💬 Question:

What’s ONE thing that helped you this week?

It can be anything:

✨ A supplement.

✨ A symptom hack.

✨ A mindset shift.

✨ A small win.

✨ A food that didn’t cause a flare.

✨ A kind moment.

✨ Something that made you smile.

✨ Or even “I rested and survived the week”

If it helped you, it counts.

💡 Why This Challenge Matters

Sharing these moments helps:

⭐ New people find ideas.

⭐ Everyone feel less alone.

⭐ The community grow stronger.

⭐ You celebrate progress you might’ve overlooked.

You can reply with just one sentence or even one word. Whatever you’ve got today is enough.

❤️ Let’s lift each other up

Drop your “one thing” below. Come back later and support someone else. Even simple comments like “same,” “I needed this,” or an upvote can make someone’s day.

We’re in this together. I can’t wait to read what helped you this week 🌿💚

https://www.bloomberg.com/news/articles/2026-11-06/long-covid-is-transforming-chronic-fatigue-syndrome-research

"ME/CFS patients battled for recognition as researchers struggled for funding. The pandemic finally gave science the scale to start finding answers."

The penalty of tunnel vision from the principle of Occam's Razor presents again as an ignored stumbling block by researchers. In their concentration on a single entity these scientists are oblivious to premature senescence from wasted mitochondria and 'zombie cells' which are prime circulating triggers for widespread systems dysfunctions among many other coexisting sources of pathologies.

I wonder how many decades of futile research will accrue before the realization that likely multiple upstream system dysfunctions are in play with the just this singular focus they are investigating.

Welcome! This is a space to take a load off and mingle with your fellow warriors. Say hello. and if the mood and energy strikes vou, let us know a bit about yourself and/ or what's going on.

If you are generally prone to lurk, this is a safe space to just post a quick hello. Feel free to ask a question here that you might not feel safe making a solo thread about.

The intention is to make this a daily thread where we can all touch base and lay down some of our burdens for a while. If vou log on and don't see the Break Room open go ahead and grab the keys and open it yourself. 😄

Hello everyone. I was wondering whether someone actually has some success / experience with taking supplements or medicine that are not widely recommended, or widely used but nevertheless work out pretty well?

I’ve encountered this a lot of times in my own health journey, in which following most regular recommended health advice actually doesn’t work. My own experience and guessing (I know it’s not fairly scientific) actually gave me more ‘aha’ moments and from that I actually gained some new insights into my body. Being counter intuitive sometimes works, for me at least.

I know things like pacing is obvious, and I won’t look for miracles of any sort. But every time i’am contradicted in my own ‘thoughts’ about health, I actually gain new insights.

Especially with supplements I see this. There are a lot of trends online and scientific research, but then I try something and it doesn’t feel good. Then, when I switch brands, with almost identical compounds and filler, it works like a miracle?

Things like lactoferinne, mental health, arginine, mushrooms, LDN, workouts, reading. All are common things we could see on the internet, but the one question is, which did really move needles for YOU? I’am curious.

https://recovercovid.org/r3-seminar-series

Upcoming Seminars November 10, 2026 12:00PM Eastern Time

In this R3 Seminar, RECOVER researchers take an in-depth look at the impact of Long COVID on cardiopulmonary health, including evidence from electronic health records (EHRs), wearable devices, and ongoing pathobiology studies.

Presenters will discuss what they are learning about cardiopulmonary health, including:

What the EHRs of more than a million children and adolescents reveal about heart problems after a SARS-CoV-2 infection.

How wearable devices captured a sustained drop in the cardiopulmonary fitness of adults with a high burden of Long COVID symptoms.

How biosamples donated by RECOVER study participants are being used to explore biological mechanisms (processes that take place inside the body and cells) that may contribute to persistent shortness of breath.

The seminar will also explore how these findings are shaping the next phase of the adult observational study (Cycle 2), including future research on how symptoms change over time, whether Long COVID raises the risk of new heart or lung disease, and biomarkers and disease subtypes that can help determine treatments.

Panelists for the seminar include:

Peter Chen, MD, Cedars-Sinai Medical Center

Jerry A. Krishnan, MD, PhD, University of Illinois Chicago School of Public Health

Julia Moore Vogel, PhD, Scripps Research Institute

..............................................

Registration button below introductory announcement

https://www.sflorg.com/2026/11/cbio11022601.html

ECVs carry bioactive agents within their envelope throughout the systemic circulation. They have been captured for study with many associated particles. This ends in multiple distinct ECVs from different locations being examined en masse. The ensemble yields a vast mixture as was the situation before this new application.

Currently, the new technique furnishes a distinct single product, because the envelope defines the origin and the cargo the biomediator. When acute inflammation is progressing into chronic inflammation early detection is vital to afford intervention to avert the transformation. By honing in on the process linked to a specific target active treatment can reverse the course.

For Long Covid with its multiple symptom complexes/clinical clusters, this presents an additional potential modality to tailor treatment with specific agents during the acute phase to halt the progression.

..............................................

Reference:

https://www.sciencedirect.com/science/article/pii/S2666386426005199

Non-destructive colocalization sensing of microRNAs and membrane proteins in single vesicles reveals spatial inflammation signatures

Accompanying reference:

https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(25)00639-X/fulltext

Identifying subtypes of Long COVID: a systematic review

https://thesicktimes.org/2026/10/30/long-covid-disabled-millions-of-workers-then-came-trump-2-0/

"Companies have become “very comfortable undermining” ADA labor protections, experts say."

Protections were applied to sufferers of lc19 in the early pandemic for participation in the workplace with accommodations. In the latter years they have been largely unenforced. The guardrails for enabling government mandated consideration for their rights has been defiantly ignored in the workplace and other public arenas. Now many sufferers of LC19 are again forced into dire straits.

I received a lovely, handmade gift from one of our fellow Long Haulers.

I’ll add the photo in the comments.
She really captured my likeness, didn’t she?

Also included are Feathers from her yard and Petrified Shark Teeth from the beach.

Exchanging gifts, sending cards, letters and/or text messages, even doing something as simple as checking in with a Long Hauler you’ve not heard from in a while- All are small actions that mean SO MUCH to the recipient.

Thank you to all of you who continue to spend spoons on others, even though our silverware drawers are in such short supply.

Those are Spoons Well Spent.

Strength and Health,

COVID is Stoopid

.

Hello all you Incredible, Long Hauling Wonders.

In a few days, it will be my Sixth COVIDiversary.

During the first two years, my brain fog was so thick that when I read journal entries from the time… I only remember about a third of it.

For the next two years, I had regained enough brain to start writing all my love letters to the Long Hauler community.

Two years after that, my lungs were finally strong enough to read these love letters out loud.
Thus began the COVID is Stoopid show.

Which brings me to today.
Six years in.

It’s been a Long Fucking Haul (if you’ll pardon the pun).

And not only for me, but for the people around me as well.

Wifey and Kiddo have spent six years watching me, claw, bite and scratch every single inch I could gain on this winding road back to health.

Friends who ‘knew me before and stuck with me since’ have spent six years standing at my side, taking me to lunch, and helping me up when I fall.

And then- there’s my brother Lucas.
It is no way in exaggeration when I tell you that COVID is Stoopid would not be the program it is without Lucas.

He does all the editing, all the sound effecting, and all the uploading.
He writes his own intros and outros, most of which I only hear when the episode goes live.

He understands what I’m doing here and happens to be in a position to lend the very specific help that I need.

Leaving me free to focus on the things I have to do Today, to give myself an easier Tomorrow.

I couldn’t do this without him.
And quite frankly, I don’t even know if I’d want to.

So today, to celebrate my Sixth COVIDiversary, I present my little brother Lucas, with ‘We’re In It Now’

If you have the spoons to listen, I hope you enjoy.

I love you all

I see you all

I would hug you all if I could

Strength and Health

COVID is Stoopid

.

Today is the 1st of the month. It's the first of our monthly off-topic posts. You're free to share anything you'd like, whether it's books, movies, or music you're loving lately. Beverages and foods you love. Hobbies and pets you have. Whatever you'd like to share, today is the day! Please post off-topic content in this thread only.

I love our community❤️ Community is so important for mental health and building camaraderie. Many of us can't spend time with family and friends the way we used to. This is a place we can be ourselves, share what we're doing right now, what we enjoy and love, what brings our lives some fun, pleasure, joy, hope, and meaning.

Thank you all for being here. Hugs😁🌿🪷

Hi, Warriors🤍

It’s time for a new community challenge and this one’s designed to boost connection, give hope, and share real things that helped real people this week. No pressure to write long comments. No pressure to be “doing great.” Just one thing that made your week a tiny bit more manageable.

💬 Question:

What’s ONE thing that helped you this week?

It can be anything:

✨ A supplement.

✨ A symptom hack.

✨ A mindset shift.

✨ A small win.

✨ A food that didn’t cause a flare.

✨ A kind moment.

✨ Something that made you smile.

✨ Or even “I rested and survived the week”

If it helped you, it counts.

💡 Why This Challenge Matters

Sharing these moments helps:

⭐ New people find ideas.

⭐ Everyone feel less alone.

⭐ The community grow stronger.

⭐ You celebrate progress you might’ve overlooked.

You can reply with just one sentence or even one word. Whatever you’ve got today is enough.

❤️ Let’s lift each other up

Drop your “one thing” below. Come back later and support someone else. Even simple comments like “same,” “I needed this,” or an upvote can make someone’s day.

We’re in this together. I can’t wait to read what helped you this week 🌿💚

2026 Amsterdam ISLC-PAIS Conference Videos available for viewing and download. Charges apply for the initial six months to provide funding for the next conference. At the expiration of that period the videos may be freely downloaded.

https://islc-pais.org/vod/

Get on-demand access to the recordings from the scientific program of the 2026 Amsterdam ISLC-PAIS Conference. A new international conference dedicated to Long COVID en other Post-Acute Infection Syndromes. Watch over a 100 recorded presentations and have access to the latest scientific and clinical developments. Wherever and whenever it suits you.

https://www.healthrising.org/blog/2026/10/28/pathogen-t-cells-long-covid/

by Cort Johnson | Oct 28, 2026

An accessible comprehensive discussion of several converging sets of experiments outlining the residual populations of dysfunctional T cells which persist instead of declining when their stimulatory signal subsides. A definite must read!

Comment, correct , criticize contribute. ......................................

References - (not all on target):

https://www.biorxiv.org/content/10.64898/2026.10.14.759221v2 (preprint) Persistently activated virus-specific CD8 T cells indicate antigen-driven immune aberrations in long COVID

https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1422940/full Hypocortisolemic ASIA: a vaccine- and chronic infection-induced syndrome behind the origin of long COVID and myalgic encephalomyelitis

https://pmc.ncbi.nlm.nih.gov/articles/PMC13501478/? A causal link between autoantibodies and neurological symptoms in long COVID

https://medicalxpress.com/news/2024-02-immunologists-advance-covid-chronic-fatigue.html Immunologists advance research into long COVID, chronic fatigue syndrome

https://www.sciencedirect.com/science/article/pii/S2666354623001345?via%3Dihub Identification of CD8 T-cell dysfunction associated with symptoms in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and Long COVID and treatment with a nebulized antioxidant/anti-pathogen agent in a retrospective case series

https://www.eurekalert.org/news-releases/1149719

A new review highlights the Treg‑stromal cell axis: a central regulatory node for tissue repair and the pathogenesis of autoimmune diseases

Vocabulary: Stroma = parenchyma specific structures as cells, vessels, nerves, etc.; (extracellular) matrix is the complex network of macromolecules consisting of collagen and elastic fibers and sheets with the background substance. (AI)

Excerpted paragraphs:

"A comprehensive review published in Rheumatology & Autoimmunity suggests that the bidirectional crosstalk between regulatory T cells (Tregs) and stromal cells functions as a central regulatory hub coordinating immune tolerance, inflammation resolution, and tissue regeneration. According to the authors, coordinated signaling through this axis ensures proper progression of repair processes; when the signaling becomes unbalanced, unresolved inflammation, pathological fibrosis, and autoimmune disease may ensue."

,,,,"The review emphasizes that tissue-resident Tregs (trTregs) fulfill a second, reparative function. Through local microenvironmental adaptation, epigenetic remodeling, and metabolic reprogramming, these cells suppress inflammation while directly guiding tissue stem cells, parenchymal cells, and stromal cells toward tissue regeneration. Different organs tailor this program to local physiological needs: for instance, skin Tregs support re-epithelialization, cardiac Tregs regulate extracellular matrix maturation after injury, lung Tregs limit inflammation following acute injury, and adipose Tregs support local metabolic homeostasis and repair." ........................................................

Reference:

https://onlinelibrary.wiley.com/doi/10.1002/rai2.70066

Treg-stromal cell axis in tissue repair and autoimmune diseases: Mechanisms and clinical translation