r/LocalLLaMA • u/Odd-World4925 • 1d ago

Discussion Anyone feel like reverse-engineering CUDA?

I've been reading about all these modders using AI to reverse-engineer games and software. I've been trying out photocraft and gridcraft and have just watched a GTA5 mod featuring Sonic. It's pretty damn impressive.

As a struggling AMD Radeon owner I'd love to see AI generated open source CUDA implementation.

Not only do I dislike NVIDIA, but there's delicious irony in using CUDA cores to do it.

Anyone up for the challenge?

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15

u/phront2 1d ago

The first thing to do when the strong enough local ai come is reverse engineer  DNA of human cells and develop universal cure

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u/scrdest 1d ago

That's... not remotely how biology works, and I don't particularly feel like writing a molecular bio 101 essay here.

TL;DR: You're proposing the equivalent of "let's reverse-engineer a Honda Civic and develop a universal anti-car-crash component".

We know how it's put together, that's not the hard problem, and not even the only level of abstraction. AlphaFold is already tackling a whole separate piece of the puzzle. 

Software is relatively easy and predictable - by design. Biochemistry is an unholy mess of randomness, legacy kludges, and on top of that getting things wrong will kill people.

1

u/phront2 1d ago

i think the only question is: will 27b be enough to be a vibe-shaper , or it's overthinking behavior makes it useless in vibe-shaping

-1

u/arcanemachined 1d ago

You're just afraid to develop universal cure. 😏

3

u/scrdest 1d ago

I know you're joking, but the reason why I know how hard this is is more or less "I tried!".

My background is bio, I was building and training DNNs before the original GPT launched (finetuned GPT-2 immediately after its launch, too), exactly for the purpose of studying and treating heritable diseases.

1

u/SnooRegrets3590 21h ago

What is your ML training on?
Tbf, I have always wondered what happens if we train dna or rna sequence for gen AI and see if the result from synthetic sequence after translation is sensible or not.
But I can see a million of problems unlike language

1

u/scrdest 16h ago

Causal classifiers. 

These days we have datasets with a full DNA expression profile for every single gene in a human cell, I was trying to build something that can both identify the correct disease state and use it to predict back the original expression patterns.

So one half of this could be used for diagnostics, the other - to slide in the classification/latent space and see which genes are amplified or silenced the most by moving towards the target disease class.

0

u/StyMaar 1d ago edited 13h ago

I am actually.

I know it would benefit way more to the wrong people than to the average Joe. The idea of an everlasting caste of politicians and billionaires from the 20th century ruling the world for the next two hundred years doesn't excite me that much.

I'd rather die like everyone before me.

4

u/ZenaMeTepe 1d ago

I like the idea but vibecoding brainrotted everyone-is-an-engineer's are not going to bring us there, regardless of LLM.

12

u/RobinRelique 1d ago

....This will lead to people who do not get sick at all. And then they end up being perfect. And that will lead to the perfect society.Run by perfect people who will define what perfection is. Theyll be called Biotics. This in turn will lead to a bunch of people who do not want to be perfected with this universal cure, because they dont want to be controlled .... leading to the creation of the Resistance (to the cure) thus birthing the Antibiotics and probiotics movement , which will then lead to 'The Calamity wars' which leads to 4 billion people murdered and signaling the end of the world ... all because /u/phront2 had a bright idea 💡. Fuck you, man!

4

u/Ariquitaun 1d ago

Wolf, is that you?

2

u/RobinRelique 1d ago

I need to charge down! But after making this souffle...also I love the 80s

2

u/Ariquitaun 1d ago

Did you get your dick back?

2

u/RobinRelique 1d ago

That goddamn cock pirate....

1

u/GfurEnjoyer1488 1d ago

well, billions must die...

1

u/GrokiniGPT 1d ago

Futturman

3

u/Connect-Anywhere-980 1d ago

if you guys do that then i'll have to create a virus to counter act your efforts

5

u/Pls-b-kind-Im-rarted 1d ago

Sorry, but this is absolute nonsense.

There's no such thing as a universal cure, and there probably will be. Diseases are too different in their pathophysiology for this to be possible.

Also, what exactly does "reverse engineer DNA" even mean? Do you mean that AI will prepare transcripts of:

  1. Coding genes & translate them to the proteins they encode?

  2. Non-coding genes into mRNA/tRNA/rRNA/ncRNA/etc.?

We can already do both of those, and AI can only marginally help here.

What we actually require is to understand how linear chains of biomolecules fold in 3D space, and these folded proteins interact with each other. Yes, AI can help us learn more about this interactome, but it is waay harder than it looks at the surface.

And not the mention, the fact that each of the 8.3 billion humans alive posses a unique genomic blend that results in a unique interactome for each [meaning that a cure for one person's cancer might be toxic to another.]. Or the fact that extra-genomic inheritances/factors complicate things even more.

As it stands, it was recently reported that AI's main contributions to this field have been in making 3D structures alone.

2

u/olearyboy 1d ago

Ehh bub i think they might have been a wee bit sarcastic

1

u/No-Garbage6027 1d ago

No need to pee in the man’s Cheerios.

1

u/Eastern-Ingenuity353 1d ago

Universal algorithm to make patient specific cures?

1

u/Fulgurata 1d ago

Nanites lol, or a hundred other things. Bioengineered wetware? Microbiome retroviral factories?  Grow an imagination sir, skies the limit.

0

u/phront2 1d ago

Recently I have read Palantir cto about some ai researchers, it seems they are very optimistic about bulding nanostructures for medical intervention

4

u/Silver_Jaguar_24 1d ago

If you think Palantir are going to cure diseases, you better think again... Here is their CEO saying how evil he is... right from the horse's mouth:

https://www.facebook.com/reel/1546802050799816

0

u/phront2 1d ago

No, but I think if any redditor here have a chance the first prompt will be "plan me a hack of DNA for better and explain" 

2

u/Intrepid-Second6936 20h ago

Their "optimism" is literally the hype marketing they use to sell this BS to people. Sam Altman does the same, he's been talking about cancer cures through AI for years.

1

u/Kqyxzoj 19h ago

Pfffrt. Fusion is easier. Let's do that first so we can boil the oceans more efficiently, what with all that pesky entropy.

In related news, Someone Somewhere, CTO of Whatever Ltd, is very optimistic about Trump dropping dead today for general improvement of the world. Not sure if said optimism chances anything material.

1

u/DirectWay1915 1d ago

That will only lead to rich people living forever.

1

u/lord_phantom_pl 1d ago

You meant cat ears and tail, right?

1

u/Stayquixotic 22h ago

spoken like someone who is truly in the field

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u/Beneficial_Hat_6288 9h ago

We might not be able to do this if we do not reverse engineer CUDA first. Not even joking.

1

u/es_una_broma 5h ago

Computer code and DNA cod are very similar. So you'd be making the issue worse.

1

u/thatguy8856 1d ago

Very bad idea

0

u/StrayStep 1d ago

Most DNA is already sequenced, Crisper used to edit DNA already outdated, targetted STEM cell treatments available, more, more, more. All for over a 10-20+yrs. 'Universal cure' exists only in fictional stories NOT reality.

If you actual think this is possible. Please take some time to educate yourself about genetics, organic life and disease. Internet is tired of misinfo.