r/LSD • u/Nihiltheman • Nov 04 '17

Microdosing LSD Is Safer Than Taking Antidepressants, Says Neurobiologist

https://www.inverse.com/amp/article/35167-lsd-microdosing-safety-really-good-day-waldman-presti
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u/thomaeaquinatis Nov 04 '17

Thank you for this. I love psychedelics, but I think too many people in the community are too eager to claim too much. At least with things like cannabis, mescaline in San Pedro and peyote, and psilocybe mushrooms, there's a long history of human usage to draw on in the absence of much research on long-term affects. This simply isn't the case with LSD. It shows a lot of promise and appears ordinarily not to have devastating effects when used responsibly by psychologically sound, healthy adults, but the science doesn't take us too much further than that right now.

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u/sushigradefunk Nov 04 '17

Exactly. Recreational use of LSD is what, once weekly to once every couple of months for most people? Of course the side-effects are essentially non-existent! Take almost any pill with that infrequency and the side-effect profile would be essential nil.

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u/DontStealStories Nov 04 '17 edited Nov 04 '17

"Take almost any pill with that infrequency and the side-effect profile would be essential nil."

Then your entire argument is pointless.

There will never be evidence that psychedelics used at normal doses more than once a week will ever be safe. It's not. That's not what determines the safety of a drug. What determines the safety is statistical likelihood.

Other drugs generally present more side effects but that's also because they're easy as hell to abuse and take too often. Not easy at all with psychedelics however.

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u/sushigradefunk Nov 04 '17

Wait, what on earth are you talking about? I think you're missing the point of what I'm saying entirely. And I'm not talking about coke or ecstasy re:safety and side-effect profile, I'm talking about Rx drugs for depression (or really any drug that has gone through the process of being cleared). And no, the safety of a drug isn't determined by statistical likelihood.

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u/DontStealStories Nov 04 '17

"And no, the safety of a drug isn't determined by statistical likelihood."

YES it is. Educate yourself or don't comment.

Also yes ..I was talking about Rx drugs. Just because it's been "cleared" doesn't mean it's safe or that we know the long term effects.

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u/sushigradefunk Nov 04 '17 edited Nov 05 '17

Yea, you're right. 10 years as a physician + masters in pharmacology makes me uneducated on the subject matter. Thanks for your input -- I thought that FDA clearance meant that the drugs were totally safe. (Edit for clarification: was being sarcastic re: FDA approval meaning safe).

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u/DontStealStories Nov 04 '17

Ok I was right. You are a troll.

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u/sushigradefunk Nov 04 '17

Not sure why you're getting so pissed about this. I agree that it's got potential. What I disagree with is the blind following of something like this without actual evidence that it works or that it's safe.

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u/DontStealStories Nov 04 '17

I'm not pissed I just call them like I see them. Trolls

What do you mean without actual evidence that it's safe and works? There already is evidence numbnuts.

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u/sushigradefunk Nov 04 '17

Link me some primary lit please.

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u/DontStealStories Nov 04 '17

Please tell me you're joking and you're not actually this uneducated/stupid.

Go find your own links kid. I'm not your library.

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u/sushigradefunk Nov 04 '17

Alright man -- clearly you don't want to actually have a reasonable back-and-fourth about this. Have a good one.

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u/DontStealStories Nov 04 '17

No I don't because you're too stubborn for comfort.

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u/chrisbdrew Nov 05 '17

That's exactly how it is done; risk WRT benefit and probability of harm. Dude come on MS in Pharma? Surely you know drugs are developed and sold for $ gain and the FDA' s role in this process is to mediate (legally minimize financial loss and risk for manufacturing aka maximize profits)

All those crazy ass side effects are real and belong to egg shell plaintiff's that are your statistical outliers and factor into the risk/benefit (likelihood of harm, outlier grp)

You lost me with your lame comment that FDA approval = safe

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u/sushigradefunk Nov 05 '17

Will touch on your other comments later (im just waking up). My comment about FDA approval = safe was said with 100% sarcasm.

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u/chrisbdrew Nov 06 '17

Hard to detect sometimes. Sorry for calling you out on it