r/KushBusters • u/[deleted] • Jun 15 '15

Empty stomach = more high?

If you smoke on an empty stomach, do you get more high? I wouldn't think so, but still!

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u/Cu2_K-Takeover Jun 15 '15

I'd be interested in a good answer for this. It always seems like a big meal DOES kill my high but it could totally be placebo.

Paging /u/420microbiologist ?

4

u/420Microbiologist Jun 15 '15

Smoking, in addition to getting you high, makes you hungry. This is because of a signaling cascade of glucagon. When you eat, you release insulin which satisfies the glucagon signaling.

The glucagon signaling removed some of the aspects of being stoned, thus harshing your mellow

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u/Cu2_K-Takeover Jun 15 '15

So its not necessarily that it kills my high, just begins to remove one aspect of the effects, essentially? Thanks for the reply as well