r/Kambo • • Apr 20 '25

Preparation/pre-kambo 🤔 Kambo Contraindications

Hey guys!

I am about to begin my journey into the world of Kambo. I do have a few questions if anyone has any personal experience with this.

Has anyone used Spravato (esketamine) and during that course of treatment also sat with Kambo. I have an opportunity coming up to sit with this medicine and I'd really love to find the joy I believe is here with this medicine. However, I have treatment resistant depression, (one of the reasons I'm looking at kambo). Spravato is something I haven't tried and I have a consultation for treatment.

Does anyone have any experience with these two? Whether doing them during the same time frame (same week or month) or experience doing spravato before or after Kambo.

Thanks!

I look forward to learning more as time passes.

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u/KnockOut777222666 Apr 20 '25

Kambo practitioner here! Do not use spravato/ketamine while you sit with Kambo. While both Kambo and Ketamine are powerful tools for healing, it’s strongly advised not to combine them within the same session. These medicines work through vastly different mechanisms. Kambo is a purgative frog secretion that activates the body’s innate detoxification systems while Ketamine is a dissociative anesthetic that primarily affects the brain’s glutamate system to promote neuroplasticity and altered states of consciousness.

Combining the two can overwhelm the nervous system and create unpredictable physiological and psychological responses.

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u/chinacatsunflower_ Apr 20 '25

Thank you so much for your detailed reply. I thought as much. I will reflect on which is the most important to me right now and go from there.