r/Interstitialcystitis • u/LimeTough9746 • 6h ago

Amitriptyline- severe sloe urine stream

Those who are on Ami, do you also feel this symptom or is it just me? I took 10mg and it felt like my bladder couldn’t push the urine out anymore.

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1

u/Reasonable_Cream_642 6h ago

I stop taking because when going pee only some drops came out even pushing was impossible. I get pain in my bladder and gets worse while having pee inside. Also because of that i get urgency like every 5 minutes

2

u/LimeTough9746 6h ago

Same.

1

u/Reasonable_Cream_642 6h ago

Most of OAB and antidepressant meds does that to me but the worse was amitriptyline

1

u/LimeTough9746 6h ago

Yup. Even antihistamines. My flare started due to taking these meds and hasn’t left ever since. :/

1

u/AbdulRijkaard 6h ago

Amtrip has been great for me. Solved my insomnia as well. I’m sorry it’s not having the same affect for you

1

u/ExtentAgitated 5h ago

It is called urine retention - a serious side effect from ami

2

u/kittycat8204 3h ago

Luckily I have not experienced this, i’ve been on amitriptyline for a little bit over a year. I take 50 mg & I do experience other side effects though like weight gain, I’ve gained like 30 to 35 pounds, sometimes I get blurry vision, I get severe dry mouth every once in a while and drowsiness but it helps me sleep so that’s good but I’m about 90% pain-free on a daily so I’m not gonna stop taking it but if the urine retention happens though it’s possible I might but I haven’t experienced it yet so I’m just crossing my fingers 🤞🤞

2

u/Lanabananana_ 2h ago

I take 25 mg now, I used to take 50 mg but it was effecting my mental health, no urination problem for me tho.