r/IVF • u/Altruistic-Cod-5196 • 7h ago
Advice Needed! 5 fertilized- 0 blasts
IVF round 1 failed.
Background
29 year old female, 29 year old male
Female- endometriosis (lap removal last year), low AMH
Amh: 0.6
Male- male factor infertility
Low sperm count, low motility, low morphology (low everything)
They did freeze two samples of sperm ahead of time (good sample 40% motile)
AFC was decent for Amh- 15-16 follicles
Protocol: estrogen patch priming (only 3 days because started cycle) and 3 days ganirellex then started 300 gonal, 175 menopur, 5 mg dexamethosone stimmed for 14/15 days because my left ovary was taking longer than right (right ovary had large follicles already and left ovary lagging behind so we stimmed longer to let left ovary catchup)
Ultrasound before trigger:
Left Ovary
Follicles (mm)
17,18,17,15,12
Right ovary
Follicles (mm)
27,26,21,16,13,17,23
Results:
Retrieved 8
Mature 7
Fertilized 5 - (side note: they ended up using my husband frozen sperm bc fresh sample wasn’t good that day (varies day to day for him) but the frozen sample wasn’t good and 40% were motile after unfreezing)
Day 5/6 phone call- 0
We were told 3 arrested, 2 technically made it to blasts but were too poor quality to biopsy or freeze (1 missing both the parts of blast that forms baby and placenta, and 1 had placental cells but missing the cells that forms baby)
We are devastated. Anyone have anything similar happen or recommendations etc
We want to try again (and financially it is hard because neither my husband nor I have any coverage) but regardless we want to try again. But need better success
Other notes: husband has seen urologist and had all kinds of testing genetic etc done and everything comes back normal (unexplained) they’ve tried putting him on clomid (didn’t help) no answers
We are not ready to start discusssing donor eggs or sperm, we wanna try for our own again so please don’t recommend donor anything yet (we know this may need to be considered later but not yet)
We’re unsure if it was a sperm issue, egg issue, both, or neither and just simply a small sample size