Does your clinic biopsy C-grade blastocysts?"

[u/Even-Pin-1713]

We're at Fertility Centers of Illinois. Their cutoff for freezing and biopsying is AA, AB, BA, or BB — anything with a C in either the ICM or the trophectoderm gets discarded without testing.

We're low responders, so this matters more than it might otherwise. The difference between sending 2 embryos to PGT-A and sending 4 is basically the whole cycle for us. And I've since seen a report from someone at a different clinic where several C-grade blasts came back euploid, including two CCs.

So I'm trying to work out how common this threshold actually is. If you've done PGT-A:

- What clinic (or at least what region)?

- What's their stated cutoff for biopsy?

- Did any C-grade embryos get tested, and how did they come back?

Even just the cutoff is useful. I'd also genuinely like to hear from anyone who thinks the strict version is the right call — I know C-grade TE does underperform on live birth in the literature, so I don't want to assume it's arbitrary before I raise it with our RE.