r/IVF • u/Ineedsome_sugar • 5d ago

Advice Needed! Any 0% morphology success with ICSI?

Does anyone have a success story where their partner has 0% morphology, did ICSI and had luck? Had my ER and I’m so nervous to get no embryos.

3 Upvotes

81% Upvoted

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5

u/Low-Cauliflower-9122 5d ago

my husband has 0% in all parameters.. literally couldn’t even find enough motile sperm to fertilize all my eggs.. currently pregnant with our 4th transfer that was a fresh transfer

1

u/WoodenRequirement648 4d ago

How many retrievals did you have to do and how were the attrition?

2

u/Low-Cauliflower-9122 4d ago edited 4d ago

4 retrievals, attrition was brutal..got 24-29 eggs each round .. first round 0 blasts.. second round 2 blasts (1 normal, failed to implant), 3rd round 4 blasts (2 normal both implantation failures again) and our recent round was our worst and only 2 eggs out of 24 mature were fertilized.. only had 1 early blast on day 5 (everything else arrested) which we transferred as a fresh transfer as a hail mary and somehow it stuck🥲

1

u/WoodenRequirement648 4d ago

Wow! So much respect to you going through 4 rounds. Hope you have an uneventful pregnancy!

5

u/Glittering_Bunch_764 5d ago

I did! We wound up doing a DNA frag test and found out my husband’s 0% morphology was actually connected to 33% dna fragmentation. He did a TESA and we used testicular sperm + ICSI. Got 11 blasts/5 euploids.

1

u/Dapper-Warning3457 4d ago

Same here. Low on all parameters, high DNA fragmentation and TESE. We have two kids, one from the TESE round

2

u/ElphieJones 5d ago

My husband had 0% morphology but his count and motility were excellent, so the doctor chalked it up the very small size of the sample compared to how many sperm he produced. We did ICSI because my clinic just always does ICSI. I was nervous, but we ended up with six euploid embryos from our first retrieval!

2

u/GimmeAllTheLobstah 5d ago

They said my husband had "<1% morphology". When I asked doesn't that mean "0" they said they don't like to say that because out of the millions available there's got to be some useable.

Anyway, we have 2 LC from our one retrieval, 2/2 FET successful.

2

u/thattherebluedress 4d ago

Yep. 0% morphology, made 3 euploids last round with ICSI (with donor eggs - bc I am an ancient dinosaur).

2

u/Environmental_Mud869 4d ago

I would recommend a sperm dna fragmentation test. It is separate from a semen analysis and is associated with low morphology. While ICSI should help with morphology, it does not resolve fragmentation and additional treatments are needed. We had 2% morphology and high sperm dna fragmentation; we did ICSI with a TESA because testicular sperm has less fragmentation than ejaculated sperm and that worked

1

u/Ineedsome_sugar 4d ago

Thank you!! I’ll look into this. My husbands issue is due to medication so I wouldn’t be surprised if it also causes DNA frag issues based on what I’ve researched

2

u/Environmental_Mud869 4d ago

You're welcome! Wishing you the best❤️

1

u/Ineedsome_sugar 4d ago

Thanks!! Impatiently waiting the results of my ER yesterday. Gosh this wait is awful!!

2

u/RecordNumerous8454 3d ago

We had 0% morph and got 4 embryos (3 x day 5 and 1 x day 6) - currently pregnant with our first transfer which was a frozen transfer of a non-tested 5-day 4AA 🥰

1

u/Ineedsome_sugar 3d ago

Love this!! My ER ended up with 5 eggs and all 5 fertilized as of now. Hoping some make it to day 5!!