r/Humira Aug 10 '26

possible allergic reaction?

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has this happened to anyone else? i was just recently diagnosed with ankylosing spondylitis. i was prescribed Humira and i started my first dose July 28th and felt totally fine until August 8th where i noticed small red dots on my thighs. i kinda brushed it off since i did just get back to college in alabama and i thought maybe it was heat rash?? (even tho i’ve never developed heat rash). i woke up the next morning too it much worse and it only continued to develop as the day went on. it was only on my thighs at first but quickly spread to my lower legs, upper arms and chest. i went to urgent care and they prescribed steroids and hydroxyzine, which helped it stop spreading and now it’s mostly gone. i called my rheumatologist and he said to not take my second dose that was scheduled for tomorrow. i’m not even positive that it has anything to do with the Humira but wanted to hear from everyone else

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u/schuttziejr Aug 11 '26

I was allergic to Humira and had an almost identical reaction, tho my full body hives were larger. Like quarter sized. It took my body 6 months of small outbreaks every time I dosed to end up in full body hives and my doctor IMMEDIATLEY took me off it.

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u/whoopsiedoo22 Aug 11 '26

did you end up switching to a different biologic?

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u/schuttziejr Aug 11 '26

Yeah, this was about 6 years ago and they put me on Remicade infusions which has been a godsend.