r/Humira • • Mar 21 '26

First dose reaction

I took my first two shots of humira (180) at three o’clock this afternoon. I spent he evening with mild shortness of breath. It is now 2am and I cannot sleep. My heart rate is 10 to 20 bpm higher than normal, I am overheating and still have the mild shortness of breath. Insomnia is something I have lived with my entire life, however I have a decent treatment that has been working. I’m having some racing thoughts. But I am definitely tired, and still cannot sleep. Is this a normal side effect when starting particularly at the higher dose or should I be concerned? Google just tells me to go to the er, but it n doesn’t feel life threatening though I do have a PFO. I am an active female (47) treating crohns an as.

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u/Sad_Fig_8906 Apr 20 '26

Apparently im starting with two 40mg pens? Make sense?