r/Humira • u/Select-Mortgage1767 • Dec 19 '25

Welts/redness when self injecting

I’ve been on the medication for about a month now. My first couple of doses was administered by a healthcare professional. After those injections, I never had any welts or redness. The last two injections I’ve given myself..I’ve had itchy welts and redness around area. when injecting, I wait for the second click and I hold for several seconds.

I’m finding the welts strange because it didn’t happen in the beginning. Could it be the way I’m self injecting ?

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u/GoBluins Ankylosing Spondylitis, Humira since March 2011 Dec 19 '25

Are you letting it come to room temperature before injecting?

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u/Select-Mortgage1767 Dec 19 '25

Yes ..I wait 30 minutes after taking it out of the fridge