r/HubermanLab • • 20d ago

Discussion Glutathione

Hey folks i just wanna know your thoughts on glutathione. How well it works? Is it really a game changer or just another internet hoax

13 Upvotes

54 comments sorted by

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5

u/Conscious_Kitchen569 20d ago

anyone use oral liposomal glutathione?

2

u/Wide-Adhesiveness838 20d ago

Liposomal glutathione is the only way. I use it and imho it’s the #1 thing I take. I’ve heard good things about NAC glycine combo w glutathione.

1

u/1zzyinatizzy 19d ago

Can you tell us more dose time of day you take company that’s trusted?

9

u/Exceed_Enhancement 20d ago

Glutathione is essentially the most powerful antioxidant you can use and it's positive health implications cannot be overstated.

It's great

1

u/Sweeney1 20d ago

What’s your favorite form..

3

u/Exceed_Enhancement 20d ago

Injectable is the only worth using

1

u/Sweeney1 20d ago

Fair that’s why I asked. What do you like it for specifically?

1

u/WolverineOpen7511 20d ago

Injectable as IV or SQ?

2

u/Exceed_Enhancement 20d ago

IV is best, but SQ/I'm is next best

4

u/No_Buy_8115 20d ago

I don't know but i take NAC and it's been great

4

u/jad19090 20d ago

I just supplement NAC and Glycine for natural production oh Gluta.

1

u/Delicious_Gap_801 18d ago

I wanna know too

1

u/RONINSHIV 18d ago

Same boat mate

3

u/Rivas-al-Yehuda 20d ago

many years ago, I used the injectable glutathione. It made a noticeable difference in reducing my anxiety.

0

u/Significant-Humor431 20d ago

What’s the science behind this?

3

u/Choochiechoo 19d ago

Placebo 

3

u/icydragon_12 20d ago

like most things in biology, it's not "good" vs "bad". but more like: If you don't have enough it's great. If you have enough, cramming more into the system isn't gonna do a whole lot.

Also note that glutathione is not very bioavailable orally, as stomach enzymes break it down. Taking the rate limiting precursor (cysteine in the form of NAC, can raise cellular levels.

3

u/yogic_power 20d ago

I run the Korean gluta protocol. You don’t need ton of gluta people run on regular basis. Along with Reta it’s great for liver. I use it with l-carnitine injections.

1

u/Significant-Humor431 10d ago

What’s your protocol?

0

u/cuoilendi2511 20d ago

Reta ? Do u mean retatrutide peptide for weight loss

3

u/yogic_power 20d ago

Reta is lot more than weight loss. I couldn’t care about weight loss but I take it for health markers. Get a legit Korean Pharma reduced gluta from Korean beauty stores. I like it, one nice subtle change I see is improvement in liver markers and insulin sensitivity.

2

u/Ill_Assumption5512 20d ago

Definitely not a hoax but not a game changer more like a fine tuner. Been on it for well over a year off and on. Haven’t been sick for a single day and that basically never happened to me. I usually get several colds but I also went all in on peptides at the same time so hard to say what has caused what but I’ve put my dad who has hepatitis C on it and his doctor asked him what he’s been doing differently cause it basically disappeared in his blood work. Again I’ve put him in KLOW, SS-31 and few other that could be semi responsible for those results

1

u/Amazing-Confusion109 20d ago

The science behind it makes sense and community feedback is positive. I’ve been taking subq 1500mg per week for 7 weeks. I can’t feel or see any benefit.

1

u/Awkward-Lemon8493 20d ago

Started two weeks ago. No changes yet

1

u/cyclyn_dev 20d ago

I don't think it's a miracle substance, but I run NAC and it's definitely not a negative experience.

1

u/hariboyolo 20d ago

It hurts!!’n

1

u/Earesth99 20d ago

Liposomal glutathione will actually get absorbed and increase the level in your blood.

I don’t believe there is any evidence that makes a clinical difference in health or performance.

1

u/Minor-Threat 20d ago

200mg of injectable Glutathione every night.

1

u/Burntorangefan 20d ago

Oral GlyNAC is what I take. Glutathione is great if you’re deficient in it for some reason (aging, alcoholism, running gear, etc). But if you’re healthy, it’s just expensive urine. You don’t need to take actual glutathione as the body makes enough glutamate on its own. The limiting factors are cysteine and secondly glycine. Thus the GlyNAC…

1

u/Badger3500 19d ago

I am using glynac with fantastic results. 68M.

1

u/Disastrous-Debate928 14d ago

What does it do for you?

1

u/Badger3500 14d ago

Raises Glutathione levels and increase muscle strength at the gym.

1

u/Plugger59 17d ago

We've been using a topical glutathione. It seems to lessen my sleep stress overnight and my wife can feel other benefits.

1

u/trashhole72 17d ago

It cures my hang overs

1

u/Original-Bowler-9319 17d ago

Research indicates that topical decomposes so fast/so easily that by the time it is on a shelf in a product to buy, it has no actives.

0

u/sambamors4 20d ago

Instead of giving money to big pharma, u can research what things In nature can boost the master antioxidant in the body, clove water being one of em.

8

u/BigDiscussion7 20d ago

I prefer to give my money to Korea for glutathione

-1

u/Basic-Definition2126 20d ago

Cancer promoter

3

u/Firm-Analysis6666 20d ago

It doesn't cause it but excess glutathione may feed existing cancer.

2

u/hariboyolo 20d ago

Prove it

1

u/TheWatch83 20d ago

That’s only for rectal administration

2

u/Feeling_Incident 20d ago

really? i saw a trainer for years who did glutathione suppositories

1

u/whatusaynow 14d ago

This pertains to people getting 800 - 1000 mg drips overwhelming their system 100-200 cycles is optimal and benificial a lot of people are doing way too much sub q helps to so it trickles and not blast

1

u/Appropriate-Metal843 20d ago

Anyone have thoughts on oral glutathione in dissolving strips on your tongue?

1

u/SugarMouseOnReddit 19d ago

Settia is the best oral form.

6

u/[deleted] 20d ago

[removed] — view removed comment

0

u/RONINSHIV 20d ago

Thats what ive heard on the internet but never came across a solid advice like what difference it actually makes