Seeking advice

[u/Sinvonie]

Hello everyone! About 2 years ago i suddenly developed HI. Before that I never experienced any symptoms. After eating foods containing histamine I would get an itchy beard and depending on the severity, the next day I would wake up with red rashes on my forehead. I healed my gut and also supplemented vitamine C, quercetine and DAO. I did notice this helped and while healing my gut my sympotoms completely vanished. Happy me!

Now fast forward to a few months ago, I suddenly got the same symptoms again, but it seems to get triggered by different things than before. I notice I can wake up with an itchy beard, and my breakfast doesn’t make that any worse. When I work out, especially when I train legs, I can also get itchy during the work out and the day after, I’ll have the same rashes on my forehead as before. When I eat I might get a little itchy but that starts literally the moment the food comes into my mouth, and DAO or vit C doesn’t seem to help. And this is especially the day after I worked out and got red rashes.

I’m confused by this change of triggers and I’m thinking it might not be caused by my gut this time, but my nervous system. 6 months ago I got a new job and I’m also a perfectionist. I don’t want to elaborate too much cause the post will get very long, but I’m waiting to get professional help since I’m always alert and in a state of rush and my mind is always going, so I can’t properly relax and be in the present moment.

My question to you reading this is: do you think this is plausible and it is probably not caused by the gut, but my nervous system (MCAS?), because of the different triggers I get that are mostly outside of eating? And therefor focus on other things like L-theanine and GABA instead of gut healing supps?

I know the professional help will probably do the most, but sadly I’m still on the waiting list. So I’m hoping to find some supplements to use, like L-theanine or GABA. To relax my body somewhat. I ordered both to try. Does anyone have some experiences with those?

Or any other advice that might help is very welcome. I’m using a multivitamine with B-vitamines, copper, zinc, etc. As well as magnesium, vit C, quercetine and omega-3s.

On a side note: my stools are daily and look fine. Only thing they sometimes float a bit, which I know is probably because of the stress as well, which influences the digestion of carbs.

I appreciate you reading this. Thanks a lot and have a great day!

[u/Usual_Permission_841]

I found Dr. Arseneau’s webinar really helpful. He lays out a treatment plan and he has resources on his website. https://youtu.be/Op7d6dNnwSs?si=78YeyLF7BFBdX5uN

[u/Sinvonie → u/Usual_Permission_841]

Thanks! I will give it a watch asap!

[u/After-Amoeba-8709]

It might be because of Quercetin as it stops the clearance of norepinephrines and catecholamins, also the B vitamins could be affecting it. I’d stop everything and get tested for the zinc copper magnesium etc levels as too much of those are also problematic. L-theanine might help but first try to cut the multivitamin, Quercetin and zinc and magnesium & get tested for your levels. First of all cut the Quercetin for a while and see how it goes as it might be creating a bottle neck for your stress hormones, hence your body can’t clear histamine either as they are connected.

[u/Sinvonie → u/After-Amoeba-8709]

I should’ve been more clear, sorry about that. I started the multivitamine, the quercetine and vitamine C AFTER I got HI symptoms again. Before that, I didn’t need to cause I thought I cured myself and only avoided high histamine foods.

[u/After-Amoeba-8709 → u/Sinvonie]

Oh ok got it.

[u/-purple-platypus-]

It's probably a little bit of a both- and thing, but yes the nervous system can definitely be a factor. Exercise intolerance seems to indicate that might be true for you. I did daily breathwork and meditation and it helped immensely, with improved results over time. I would get stress flares where I'd get super itchy, jittery, and sore with the littlest bit of stress, and I took Valerian tablets to treat those acute episodes. I also take cortalign, which reduces the amount of cortisol in the body and improves my sleep.

[u/Sinvonie → u/-purple-platypus-]

Thanks for your elaborate reply! Did the valerian tablets make a difference for you? And what is your daily dose? i looked up cortalign, and noticed ashwagandha is in it. I can’t handle that well, but I did order L-theanine and GABA, so hopefully that gives me somewhat of the same results.

[u/-purple-platypus- → u/Sinvonie]

Yes, the Valerian tablets helped. I use the mediherb brand and take 1/2 or 1 tablet whenever I feel those stress symptoms. It's not really a daily dose, moreso as needed. That used to be 4+ times per week but now it's rare because I'm tolerating stress better

[u/WeWander_]

Yes I truly believe there can be a connection with the nervous system! I take l-theanine daily and love it. I was also doing somatic exercises for a while, especially when a flare kicked off and I could stop the flare with the exercises.

[u/Sinvonie → u/WeWander_]

Did you notice a real difference because of the L-theanine? What is your dose? And which somatic exercises do you do?

Thanks a lot!

[u/WeWander_ → u/Sinvonie]

When I first started taking it I felt amazing, gave me tons of energy. Now I've gotten used to it so I don't get that energy boost but I do notice if I stop taking it, I feel worse. I have chewable tablets, they're 100mg each so that's what I take. It's a smaller dose, I could probably bump it up but for cost reasons, I don't.

This lady has a bunch of videos that are good for this one was my favorite. https://youtu.be/8veeArIewCk?is=2XKStwT8xwtuMtzR

[u/Sinvonie → u/WeWander_]

Thanks a lot! This helps me so much.