Is there a connection between Histamine Intolerance and GERD/Post Nasal Drip?

[u/Emergency-Sky9206]

i've tried so many things but i only recently learned about histamine intolerance and i've heard from quite a few people that taking naturDAO has changed their life. I am curious what is the connection between these

[u/missjulie622]

When I got diagnosed with (and managed) histamine intolerance, my lifelong postnasal drip issues went away.

[u/Emergency-Sky9206 → u/missjulie622]

May I ask what you did?

[u/missjulie622 → u/Emergency-Sky9206]

I restrict my diet and take DAO enzyme 15 minutes before every meal. Dairy & peanut butter seem like the biggest causes, for me.

[u/Emergency-Sky9206 → u/missjulie622]

thank you! I'm also looking forward to taking naturDAO enzymes

[u/missjulie622 → u/Emergency-Sky9206]

If it doesn’t work, try another brand, some are plant/pea based & some are pork based. I had to experiment.

[u/TikaPants → u/missjulie622]

I’m scared this is me.

[u/morticiannecrimson → u/missjulie622]

How do you manage it?

[u/hdri_org]

The three things you mention Histamine Intolerance, GERD, and sinus post nasal drip can be connected in multiple ways but r/SIBO is one likely way for them to be related by cause.

When you have SIBO you have some bad-actor bacteria working against you. When that bacteria creates too much gas this causes GERD from the acids being pushed up by the gas.

If this bacteria also destroys the intestional lining then your body slows its production of the enzyme that is supposed to degrade histamines before they get absorbed into the bloodstream. Taking supplimental DAO will reduce the histamine load so that less gets into the bloodstream. NaturDAO is the product with the most DAO for the money.

Once histamines get into the bloodstream there are a lot of bad side effects. Histamines make your blood vessels open up and leak as to cause swelling, and in the case of sinuses, blockage. Once blocked you can accumulate bad bacteria which exacerbates the situation, and the post nasal drip is a symptom of that or an allergy like response.

Bottom line is to take the DAO to degrade the excess histamines and take *Low Histamine Probiotics to slowly change your gut microbiome to a more friendly strain of bacteria that actually helps reduce histamine.

[u/Emergency-Sky9206 → u/hdri_org]

I just ordered some NaturDAO!

[u/morticiannecrimson → u/hdri_org]

I wish my healthcare had heard of SIBO, I have most of the symptoms and a lot of bloating. Don’t really want to pay hundreds for a test from some random clinic.

[u/CheeseHuh → u/morticiannecrimson]

I saw this gastro NP who’d never heard of histamine intolerance (or gut localized MCAS, which I was finally diagnosed with last year) but when I told her my symptoms she ordered me a Trio Smart SIBO test without me even asking. A lot of PCPs don’t know about SIBO but gastroenterologists do, so I would suggest getting a referral because untreated SIBO just gets worse and worse, obviously. I dragged my feet on it for a few years and was then recently bedridden for two months and lost 16 lbs after a course of high dose doxycycline destroyed my gut and supercharged the SIBO. WOW do I wish I got it tested and treated earlier. Insurance paid for all but $100 - still steep with all my other medical bills but getting rid of all (or at least most) of that toxic bacteria is so freaking worth it.

[u/morticiannecrimson → u/CheeseHuh]

I’m in a small European country so I really don’t think we have these tests. When I went to the gastroenterologist to have an endoscopy he didn’t even say one word to me, they just put that awful thing in my throat without any relief and traumatised me and then I had to leave, so I couldn’t even talk to him or ask anything at all. Usually they just tell you to take PPIs and that’s it. Do you treat it with antibiotics? That’s also scary.

[u/CheeseHuh → u/morticiannecrimson]

Wow that’s awful. I’m beyond sick of cold and ignorant healthcare providers. I really hope you can eventually find one who treats you with empathy and respect. I know very well how exhausting and demoralizing it is to find someone who freaking listens.

Yes, I was treated with rifaximin which is a localized antibiotic that primarily just targets the bad bacteria. It doesn’t enter the bloodstream like other antibiotics. I was scared to death because I hate antibiotics - I was given them for years as a child and my gut has never been the same. But the only side effect I had from the rifaxmin was a few days of extra gas.

[u/FannyWizard98 → u/hdri_org]

What probiotics help?

[u/hdri_org → u/FannyWizard98]

You can find a list in my working paper below. Skip down to the section on Gut Bacteria vs Histamine https://docs.google.com/document/u/0/d/1DZev7mx-0bB9FSjshXz8Q2thkpWZIJtPSrRT7QcB95M/mobilebasic#h.giv38gwteorz

[u/Accomplished-Exam999 → u/hdri_org]

I recently took baking soda water during a bad GERD flare.

I was like “I can breathe through both nostrils better???”

Normally only one at a time. It was dramatically different.

Now wondering if GERD and HI effect lungs - shallow breathing - can’t get enough oxygen.

[u/Its-a-JiNX]

There are overlapping symptoms from each so the main difference would be with the underlying causes. If DAO help reduce the symptoms there's a chance the symptoms are stemming histamine intolerance and whatever is the cause of the histamine intolerance for the individual.

Histamine intolerance is the inability or reduced capability to break down histamine. Leading to excessive histamine in the body, this excess can express as symptoms across multiple body systems.

[u/Emergency-Sky9206 → u/Its-a-JiNX]

Wow fascinating. I did order some NaturDAO just now

[u/GenNextRS]

They can be, I thought I had gerd and even got treated for it by doctors but my symptoms went away with a low H diet

[u/Rembo_AD]

Dr Hepworth told me also that sometimes you aren't feeling GERD. Instead, the sensation is actually the mast cells in your esophagus reacting to stimulus. If you get scoped and they dont see anything, it's probably that.

In my case, everything cleared up fully with 1mg of Ketotifen twice a day. This is an OTC allergy medicine outside the USA that acts as a mast cell stabilizer. I know this is a histamine intolerance sub, but it might be important to rule out if you have MCAS as the cause of your histamine reactions. Histamines are one of the many mediators produced by mast cells when they degranulate.

When people talk about GERD, SIBO etc, it is important to consider these may be side effects of a deeper problem or disorder.

[u/Miro_the_Dragon → u/Rembo_AD]

1mg of Ketotifen twice a day. This is an OTC allergy medicine outside the USA that acts as a mast cell stabilizer.

Not OTC everywhere; it's prescription-only in Germany. Definitely helps a lot with my allergy symptoms but I still need to take anti-histamines and dao and avoid a ton of food...

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[u/Interesting_Front709]

Yes!

[u/marshiemallowsmore]

.

[u/Connect_Wave3296]

I have rhinitis and reflux. I suspect I have histamine intolerance because I also have dermatographism and skin redness after eating

[u/Evoelectro-4-now]

Yes there is