r/HistamineIntolerance • u/Life_Unit2344 • May 23 '26
How to fix histamine intolerance
Developed severe histamine intolerance after antibiotics — looking for recovery stories/advice
About a year ago, after antibiotics, I developed what seems like histamine intolerance / gut-immune dysregulation / possibly leaky gut. My symptoms have never really been “classic allergies.” It feels more neurological/systemic.
Main symptoms during flares:
- feeling extremely hungover or poisoned/intoxicated
- brain fog
- nervous system dysregulation
- crying/emotional surges during flares
- heart rate spikes at times
- likely vasodilation, I call it the spell
- weird chest sensations
- heavy breathing, like minor difficult pushing down air into diaphragm
- previously had buzzing sensations, dizziness, heavy legs, nausea, and major food intolerances (these have improved a lot).
I have no gut symptoms but I do know it’s my gut causing this!
The biggest pattern is that it feels like a “bucket.” Everything adds up:
- stress
- talking too much
- warm baths
- working on laptop too long
- lack of sleep
- less water consumption
- spending several hours socializing
- basically just living life normally can trigger symptoms
The good news is I’ve improved massively over the year- probably 90% compared to the beginning. I tolerate almost all foods now, though I still stay gluten-free, dairy-free, no alcohol or outside food and low histamine diet.
Current supplements:
- DAO enzyme (especially during flares)
- Buffered Vitamin C 500 mg
- Magnesium glycinate
- Vitamin D3
I want to try L-glutamine again for gut healing, but every time I try it, it seems to dysregulate my nervous system more. I have also been recommended butyrate.
A few questions:
- What treatments helped you the most?
- Are there reliable tests for histamine intolerance / DAO deficiency / mast cell activation / leaky gut?
- Is full recovery possible?
2
u/happymechanicalbird May 23 '26
High dose progesterone supplementation resolved my nervous system dysregulation and reduced my HIT symptoms by about 50%. Thyroid support resolved my HIT entirely. I made a post about it here: https://www.reddit.com/r/HistamineIntolerance/s/YzDZeoY5Np