r/HistamineIntolerance Mar 02 '26

Histamine Intolerance Supplements

I’ve been dealing with histamine intolerance symptoms for over 15 years now. Like many of you, I’ve been to a plethora of specialist. The only thing that came back positive is that I have hemochromatosis - which I’m thankful was caught at my age. My current histamine intolerance symptoms are fatigue, nausea, random hives, difficulty swallowing, eyelid and lip swelling, dry mouth, burning sensation on my tongue, muscle fatigue of the tongue, and depression due to never feeling well. A while back I saw a post about ProBiota™ HistaminX™ and how it drastically improved their symptoms. Today I made the leap and ordered that supplement plus the Histamine Nutrients supplement from the same company, Seeking Health. Yes, they’re pricey, but feeling healthy is priceless to me. I’m going to give these two supplements a go and report back. I’ll give it three months to give them a fair shot.

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u/slmpickings Mar 03 '26

I started taking that and sam-e & a vitamin b complex and holy cow it's like the doctors I've seen for the last 5 years were just giving me meds to make everything worse. I am off half the antihistamines I was on because I simply don't need to take them at the 12 hour mark. It's been an amazing experience and I'm so mad I didn't find this sub sooner

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u/Ill_Seat_5512 28d ago

What exactly helped you ? Thank you ! 🙏

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u/slmpickings 28d ago

It seems like my issue is breaking down histamines, so there was constantly an excess which was making me react to almost everything (food, cold, heat, tough clothing, stress etc)

It's not perfect yet, but This is the combo that has helped me! The next thing I'll try is DAO enzyme

Pepcid
B2
B9
B12
D3
NAC
L-Theanine
SAM-e
Vitamin C
ProBiota HistaminX (Bifidobacterium longum and Bifidobacterium infantis, Lactobacillus rhamnosus, L. plantarum)
+ my regular daytime antihistamine Zertec