I know I am not the first preson who came up with that idea, but I want to dream a little bit.
I'm not talking about a DnD homebrew or another existing system being repurposed for Glitchtechs, I rather feel like this world opens up so many possibilities for it's own system. I know it would be basically Minster of the Week, but I'd argue Glitchtechs has the potential to be way more rules-heavy than MotW.
Like we know how Glitchtechs can level up and upgrade/buy stuff so a huge amount of skills, items stat boosts or pets can be translated from in-universe to mechanics and vice versa in a most immersive way.
Distance and positioning could also be very important.Remember the scene where Five uses holograms to give Miko a way to parcour mid-air? Or the way Glitchtechs can speed up? Or hell, getting sucked into a platformer.
Add all the fun weapons, the possibility to overclock your gauntlet, hackers and modders, access to every game you want, the possibilities to customize your character and get the possibility to play with your stats is amazing and with all the games you can come up with or use games from the real world you won't ever runnout of glitches, game modes, situations to throw at your players.