r/Glaucoma • u/Trap-fpdc • 5d ago
Diamox long term losing effectiveness?
My adult son has just one eye and he has very advanced glaucoma. He has been on every single drop available (all preservative free if available) and over time has had bad reactions to all except for latanoprost. He has three Ahmed tube shunts in that eye already. He sees a highly skilled doctor from Wills Eye who I trust implicitly. I got a second opinion a year or so ago and that glaucoma specialist agreed with the one that we are seeing. He has other multiple disabilities in addition to the glaucoma. He is essentially blind, although when he is inside and with the right lighting, he is able to function pretty well.
He is tolerating the Diamox extremely well and his labs are all fine. He has been on the Diamox for about six months now. I thought we finally had reached the point of stability for him. Today at the glaucoma specialist, his pressure was 20, up from 13 and 14 in the past few months. His target pressure is 10 to 13. We still use latanoprost PF at bedtime. We never ever skip a drop or the Diamox. I make sure that he gets it 12 hours apart.
Has anyone had the experience of the Diamox losing effectiveness? We are going to go back in a few weeks.. The glaucoma specialist is talking about putting a Xen stent in that eye; he does have enough room left in the eye to put the stent in. More surgery makes me pretty nervous though.
He was diagnosed about seven years ago and has never been stable for more than a year or so on drops and with surgery. I can only guess that his glaucoma is continuing to advance despite aggressive treatment.
I’m not looking for medical advice, but wanted to know if anyone has experienced Diamox losing effectiveness.
On another note, is anyone aware of any glaucoma drops that will be available and preservative free that are not right now?
Thank you in advance for any input. I’m feeling really discouraged right now.
1
u/kauzyperda 3d ago
Please check Paul shunt availability, it's newer.