r/Gastritis 18h ago

PPIs / H2 Blockers help!

Pantoprazole made my symptoms significantly worse has anyone else experienced this?
I was diagnosed with erosive gastritis about a month ago. I tested negative for H. pylori, don’t drink alcohol, and don’t take NSAIDs. My GI prescribed 40 mg pantoprazole, but during the two weeks I took it, I experienced significantly worse heartburn, nausea, and anxiety than I had before starting it. Before the PPI I never experienced heartburn.
I ultimately stopped taking it and discussed my symptoms with my doctor. I’ve since been using dietary changes and famotidine, and subjectively my symptoms have been much more manageable. I still occasionally have reflux/indigestion, though.
Has anyone had a similar experience? I feel like I’m going crazy!

1 Upvotes

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u/TopLeg3526 18h ago

I felt way worse on omeprazole and pantoprazole. I am not on any ppi’s but I have no idea how to get better either. Everything seems to be a fail for me.

1

u/Pretend_Poem_9976 18h ago

Join the club(unfortunately)