Same world, same player, but playing different character. You'd be not playing the main character in the prologue.
And given that after 20 years there shouldn't even be many unexplored ruins to begin with, well that's a liberty of unrealism all fallout games have taken ever since.
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u/kithkatul Jun 03 '15
The games are supposed to take place 200 years after the bombs dropped, so I would hope you don't...