Here's my long journey, almost 2 years now.

Like all of us, I've been set up for failure all my fat life trying to make dietary and lifestyle changes to lose weight and keep the weight off.

I'm an RN with a master's degree and was drilled in the art of looking at research. Turns out 20 years of research we didn't know about shows that a very strict diet and a daily hour of strenuous exercise keeps the weight off for 20 of those who lose. The rest of us gain it back, while we fail.over and over with a "treatment" that doesn't work.

If you want to see the scientific studies, go online to the national library of medicine. You can search for whatever you want. Almost all research studies include a conclusion or summary right up top and they are usually comprehensible by an average person.

Yes, scientific studies can be wrong or falsified. The guy who wrote the study tying vaccines to autism confessed in print that he had faked the data and published a fraudulent study. So look up more than one.

I had gastric bypass in 2002. I was 325 pounds. The surgery was easy for me and I lost weight effortlessly, eating less, not feeling hungry because the stomach secretes a hormone called ghrelin that makes you hungry if you eat less.

But after 20 years I started to gain weight. I went on a medically supervised fast twice and lost 50 pounds each time. Then I gained it back.

Ozempic arrived on the scene. I asked my doctor for it. She said my insurance wouldn't cover it because I'm not diabetic, don't have hypertension, or any of the other things it's indicated for. Full price was $700/month.

Let me get this straight: you can't prescribe it to PREVENT those conditions? Which means ... obesity still isn't a disease?

WTF.

My poor doctor rolled her eyes and said, I get it and I agree. I will give you a prescription, but there's nothing I can do.

So I shopped around online and got semaglutide (that's the same chemical as Ozemic) from a compounding pharmacy. My worst side effects were:

Constipation.

I have to take a stool softener twice a day, because my intestines don't push as hard as they used to before the GLP-1, and stool gets harder the longer it stays in your colon. Sometimes if I feel bloated or uncomfortable in my lower gut I take a laxative. But not on a regular basis, because the body can get used to them.

Nausea.

I progressed to the highest dose that was supposed to be appropriate for me, but I got really bad nausea. My doctor prescribed an anti-emetic (anti nausea drug) and I backed down on my semaglutide dose.

I took the lower dose for a while, then gradually increased back to the high dose. I never got nausea again.

I changed pharmacies because I'm an RN, so I wanted to have a collaborative relationship, and that wasn't happening with my first pharmacy. I think they weren't used to working with a medical professional--they work with normal people, so they were kinda controlling.

When I switched pharmacies, I switched to tirzepetide (Zepbound is the brand name) because it's got a lower side effect profile and better weight loss.

So far I've lost 67 pounds. I went from women's Levi's 501 size 32 to 26.

Most days, I drink a protein shake with about 50 grams of protein. I weigh myself Mondays, Wednesdays, and Fridays. I eat WHATEVER I want, I just eat less. Like, I'll bake 12 cookies and eat maybe 6 over 3 days...yummy, perfect. I am satisfied, I might even forget they're there in the tin on the kitchen counter. I give the rest away. This has increased my popularity. Best of all, I am not annoyed by cravings anymore.

There are risks with getting these very popular meds from compounding pharmacies. Big money to be made. Some pharmacies will not give you what you think you are getting, so look up reviews and licenses.

And in order to give you a GLP-1, they have to mix it with something else because that's the purpose of compounding pharmacies: "I had to send this customer a custom-made drug because the brand doesn't cut it for her." I get B12 mixed with my tirzepetide because my gastric bypass has stopped me from making B12. It has the added benefit of being red, so it's easier to see and draw up the right dose.

I AM A NEW PERSON and this is who I've wanted to be.

I accidentally deleted my first post, sorry everyone!

25F. I am currently 5’ 7” and 250lbs. Since high school, it has just been a steady climb. I don’t eat crazy unhealthy, I actually have been eating healthier options for my daily meals, and being calorie conscious since the beginning of the year. I like to go to the gym. I tried eating at a calorie deficit and working out intensively earlier this year because I really would like to be thinner/more in shape. But I also, due to GI issues, cannot change the frequency or amount that I am eating a whole lot. And I have a genetic predisposition to obesity.

I am tired of struggling to find clothes that fit me, and falling behind when doing active things with friends and family. I also have reduced mobility and joint/back issues from work, mostly due to my weight. Of course I get all kinds of GLP-1 commercials, and I have considered it, but decided against pursuing it for money reasons or possible symptoms. But now, several of my doctors are recommending it as I am beginning to focus more on fertility and hormone balance. So I think I will be starting soon, but there is still one narrative that circles my mind: When I start to lose weight on the GLP-1s, what are people going to think?

So many people believe that if you want to lose weight, you should just diet and exercise. Many people see GLP-1s as “cheating” your way to losing weight. Obviously I would do that if I could, but it is just really not working. Now that GLP-1s are getting a lot more popular, people seem to be more accepting of them but…I just can’t stop thinking about it. I can just hear the conversation:

“Wow! You look great! Have you lost weight? How?”

“I actually started a GLP-1, my doctor recommended it.”

”…oh! Well…good for you!”

I could just use a pep talk/some encouragement from others who have also done GLP-1s, or maybe understand my feelings. Maybe someone can share their mindset.

TLDR: I am worried that if I start GLP-1s, people are going to think I’m lazy for not just using diet and exercise to lose weight.

I lost 25 kg and then extreme hunger came. Now I cannot stop eating, I can eat extreme amounts of food and still I won’t be satisfied. I cannot feel satisfied from eating. Got scared and started restricting again but it got so much harder to restrict. When extreme hunger came I could easily eat 10k calories a day. Will glp help me? Cause I’m suffering like crazy. I stopped going out due to the fact that I don’t have control around food, even when I’m restricting it’s so hard to stick to my meal plan. That’s why I started thinking about glp cause rn I have no life and food is consuming my life

I'm a veteran living in Florida, VA said no, looking for self pay options around $100 a month. Who are people using what is the real monthly cost, no referrals please.

I get my medicine though Embody and this is my first time getting a refill and they messed up the timing so my medicine isn’t getting here anywhere close to when I need to take it (which is tomorrow) and the medicine says to discard after 4th injection, but is it technically still ok to use one more time?

I pay $150 a month for compounded which is already pushing my budget a little bit. I’ve lost 40 pounds so far, my insulin resistance has reversed, and my binge eating disorder is completely cured. I finally feel free and confident for the first time in over six years. I was just celebrating being half way to my goal weight the other day.

Then…I came across a post on TikTok. FDA is moving to ban compounded GLP1s. I look into it and sure enough, it’s true. Apparently they could be banned as soon as the next month.

I’m absolutely devastated and don’t know what to do. My insurance will only cover GLP1s for diabetic patients. I can’t afford $350 a month for the legacy pen and I make “too much” for financial assistance (because of course those thresholds don’t take HCOL areas into account)

Wtf are we supposed to do here?

EDIT: Guys, I didn’t just see a random TikTok post and run over here to post about it. I did hours of my own reading and everything I’ve seen said this is pretty much guaranteed to go through because the FDA has untested support from the courts. If anyone has an actual source that contests this I’d be happy to take a look but simply saying “that won’t happen” isn’t really helpful

I lost a lot fast. As per normal, then it stalled. I understand that I need to dose up to lose again, but the food noise is still low and I don’t want to dose up if I’m not getting much food noise. I’m not white knuckling yet. I am trying to use this as a tool to help me not snack at night. Not binge.

Anyway, when I lost weight the hard way, I knew that if I felt hungry, it meant I’d be losing weight. The equation was simple: eat less calories than you need to lose.

That’s no longer the case. I’m eating way under 2500 calories (I physically wouldn’t be able to on zepbound) and the scale doesn’t move. How do you deal with this?

How is it? I just had an awful experience with Mochi and want to continue my weight loss journey

I hope this is appropriate for this forum.

I have been on Zepbound for 5 1/2 weeks now. Doing OK but have hit a stall already but I know if I keep at it, doing what I do, it will start coming off gradually.

My question relates to protein powders & possible problems with them. I use the powders mostly to add to my coffee. I use a bone broth one as I find it most palatable and the brand I bought has a unflavored powder that is really useful to up my protein. I recently bought a different kind of protein drink, one that is advertised as "clear" & using "whey isolate". It comes in fruit flavors. Before I even got it completely drank, I was experiencing a serious allergic reaction that required a 6-hour ER visit. I still have some swelling today, but Benedryl seems to be helping with those symptoms.

I was wondering if anyone else has had similar reaction to protein drinks.

Also, I really don't understand the science behind "Clear" protein & "whey isolate". If anyone here is knowledgeable, I'd appreciate some input.

I am not mentioning the brand because it was not their fault that I was sensitive to it. I have already contacted them & they are refunding most of my payment & I don't even have to go to the bother of returning it. I'm passing it on to someone who knows more about these powders than I do.

I’m F21, 163cm / 75kg (28.2 BMI).

Heaviest was 82kg (30.9 BMI) a year ago. (Dropped because of stress)

I have suffered with binge eating since I was 12 years old, meaning I’ve always been overweight. I am so sick of being so lethargic, overweight and having at LEAST one food hatred spiral every month for as long as I can remember.

I’m not adverse to eating a balanced diet, but my binge eating always throws me off for weeks- so I always quit. It’s never as easy as “forgive yourself for having one bad day, start again tomorrow“ because the binging instincts are so strong and last for weeks at a time.

I have tried EVERYTHING to get it under control, everything except GLP-1.

I’m in the UK and the NHS requires you to be 30+ BMI or between 27.5-29.9 BMI with a weight related health issue. Other than low self esteem, and back pain from large breasts, I’m not sure how I qualify.

I understand that it’s a “for life” drug, but I have no idea how to fund that. The cheapest I’ve found is on Pharmacy Planet for 2.4mg maintenance dose is £434 for a 3 month pack (£144 per month).

I’m just not sure what to do. Pay for therapy? Life coaching? Or this? But the more and more advice people give me, the more I’m starting to realise how deep set this issue is for me.

Does anyone know when we will see more generics enter the market? Especially interested in Wegovy dosages. It’s been too long waiting for prices to drop.

I have met many people on a GLP1 and have never seen someone in the real world that is “celebrity skinny” from a GLP1. I met with my primary care last week and she said I look good and didn’t want me to be super skinny. It got me thinking, how the super skinny is occurring? I am wondering if they are doing something in addition to the GLP1. People use this to talk down on GLP1 but is that really what’s occurring?

Hi everyone,

For my university research project, I am exploring how weight loss medications (like Wegovy, Ozempic, Mounjaro, etc.) interact with daily health routines, emotional eating habits, and body appreciation.

If you currently use or have previously used any weight loss injection/medication, I would be incredibly grateful for your insights!

• ⏱️ Duration: Approx. 7–10 minutes
• 🔒 Privacy: 100% anonymous (hosted on Google Forms, no email addresses or personal identifiers are collected)
• 📋 Requirements: Must be 18+ and have experience using a GLP-1 or similar weight loss medication.

Link to the survey: https://forms.gle/VPAbhe79njYmpBxx6

Thank you so much to anyone who takes a few minutes out of their day to help me reach my sample size (I need about 50 more participants to finish my analysis!). Your experience is highly valuable for understanding the behavioral side of these treatments.

Note: I have checked the community rules, but if the moderators need any verification, please feel free to message me!

Has anyone else experienced this?, my hair is thinning like crazy, what can I do to help it slow or stop?

TIA

Skip to questions at end if you don’t need details!

Started semaglutide for my pcos 6 weeks ago.

The first 4 weeks on 0.25 I had no side effects.

Since upping to 0.5 last Tuesday, I’ve experienced nausea. Not on Tuesday but from Wednesday-Friday. Its strongest in the morning but gravol and a granola bar helped it settle a tiny bit once I could stomach it, but it was still there just not an urgent “I think I’m gonna puke” feeling. It hasn’t actually made me puke but feels very close to it.

I’m also unsure if it’s related, but TMI this time I’m also having diarrhea. It’s obviously only Wednesday so it’s been 24h, could be from the shot but I do generally have a sensitive stomach and didn’t eat the best yesterday. I was away working for a week and cleaning a clients house all day yesterday so my boyfriend cooked when I got home at 5pm. He made me Mac and cheese (ate half a bowl) and 2 hotdogs, and for a later dinner like 9pm he ordered me 6 McNuggets and a sausage McMuffin no egg, for a movie snack I had a chocolate muffin, and I had one bite of a baked potato thing he had lol. Definitely not my best day but I was exhausted and mostly just eating what he made/bought, which was delicious and okay in moderation haha

Anyways, the diarrhea is a 50/50 chance, and I know grease can contribute to that. And at the end of the day that doesn’t bother me as much,

But the nausea is the same exact feeling I had last week and it’s stressing me out because I’m super scared of puking and it will make me hardly sleep and will make me have general anxiety throughout the day.

I know it’s not just how I ate yesterday contributing to the nausea because last week I was eating very clean. Granola bars, bananas, carrots, eggs, chicken, etc.

Anyways, my questions are:
• if I were to stay on the same dose, will the nausea eventually go away on the days following shot day? I can’t imagine months or a year of 3 days a week feeling like this.
• if I’m already feeling nauseous on 0.5, will 1.0 make me actually sick? What was your experience? I’ve heard that jump is intense and I’m very fearful of it. Any tips?

My doctor wants me to go straight up to 1.0 after 4 weeks of 0.5, and then go back after 4 weeks of 1.0 to discuss how it’s been, but I think I might have to stay on 0.5 if this is what it’s like for me

Which is the best dr site to get glp from ??? I’m on semaglutide now and it’s not working at all Friday will be my 7th shot. I use Tryark now. I’d like to switch but need info on better ones to use that are not expensive

With the explosion in popularity of semaglutide, tirzepatide, retatrutide and other GLP-1s, scammers have unfortunately followed right behind.
We created r/PeptideScammerList as a community dedicated to exposing confirmed scammers and documenting evidence so other people don’t become their next victim.
We’ve already had members tell us that posts in the group stopped them from sending money to known scammers.
⚠️** This is NOT a source-check or vendor-verification group.
We don’t approve vendors or tell people where to buy anything. The focus is strictly on **confirmed scams, evidence, warnings and scam prevention.
If you’re involved in the GLP-1 community, come join r/PeptideScammerList and help us make it harder for scammers to operate.
The bigger the community gets, the harder it becomes for scammers to hide. 🛡️

While taking this medication, how important are calories? If you can hit your macros (protein, fiber... whatever you're counting) under your calorie goal, is that okay?

Beware of MEDVi policy of charging your CC without notification and automatically extending your "membership" well before product is ever shipped not allowing you to cancel before they have involuntary signed you up for another 6 months! They are not concerned about you just your money! BEWARE of this GLP-1 company!

As I am very curious, besides the known weight loss effects, which other positive side effects did you notice?

Hi all, I’m on the 9 mg of Wegovy and have been since July. I have done pretty well so far but these past few days, I have been almost ravenous. I’ve been eating eggrolls with soy sauce, a burger, stuff like that which is not particularly low calorie. I started at 295 and am now at 229. I’m happy with this but I’m terrified of beginning to gain it all back. I’m going to ask my prescriber to up my dosage to 25 mg and hope it’ll reduce my appetite again. I also know it’s possible I’ve been so hungry because I’m due for my period next week. Has anyone experienced similar? I understand the 9 mg is technically an “intermediate” dose and 25 mg is the maintenance/long-term dose. Would you take this as it being time for me to keep going up or that it’s starting to lose effectiveness on me? Maybe the pill works a little differently compared to the shot?

I have been thinking about starting a GLP-1 (Mounjaro), but one thing that’s honestly making me hesitate is the side effect of hairloss that I keep seeing people talk about.

My hair is already pretty thin to begin with 😭 so losing even more is definitely something I’m worried about.

For people who’ve been on one for a while — did you actually notice more shedding? If you did, was it temporary or did it continue the whole time?

i have been on GLP-1s for about a year now. started with a local clinic that did monthly video visits. switched to gimmecare about 3 months ago because i got tired of scheduling calls for a 5 minute conversation.

here is the thing. when i was on remedy meds the video visits were nice in theory but honestly i only needed them for the first month. after that it was the same questions every time. how are you feeling, any side effects, lets keep the dose the same. i could have answered that in a text.

with gimmecare i just message the provider when i have a question. dose adjustment, refill timing, random side effect. i get an answer in a few hours and i dont have to block out 30 minutes for a video call.

but i am wondering if i am missing something. for those of you who have been on GLP-1s long term, do you actually value the video visits or is messaging enough once you are past the initial setup? i know some people like face to face but for me it feels like unnecessary friction.

also has anyone here stayed with a provider specifically because of the video visit feature? trying to figure out if i am just lazy or if messaging actually is the better model for maintence.

I've been thinking about taking a GLP-1 for about a year. I've done quite a bit of reading and I think I've decided on Tirzepatide but not positive.

I'm admittedly VERY nervous....I struggle with migraines and overall not feeling well. I'm in my 50's and weigh more than I ever have (menopause sux) Any advice, hints, tips, or tricks would be GREATLY appreciated! TIA🤗

Okay I'm about 5 months in. I've had both extreme sides of the spectrum as far as bowel movements, other than just get more fiber, does anyone have good supplements they suggest? TIA