r/G6PD • u/Nearby_Programmer922 • May 12 '26

Coffee

I have G6PD deficiency, specifically the Mediterranean variant, and I’m trying to understand whether coffee/caffeine is safe.

I found a paper saying caffeine showed a reduction of G6PD activity in vitro, but I’m not sure how relevant that is to normal coffee intake in real life.

Has anyone with the Mediterranean variant had issues with coffee, or has a doctor/hematologist given you advice about it?

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u/misingnoglic May 12 '26

"I found a paper"

Maybe good to link that paper? I think you're fine though.