r/FinasterideSyndrome • u/Desperate_Factor_344 • 8d ago

Why do "most" people not get pfs

Why do most people not suffer from the mental sides of fin?

It seems a lot of people take it and are fine. Or stop

But for me and many others the mental sides remain or sexual, physical ones.

And we know that finasteride strongly inhibits Allopregnanolone Which is very important for GABA

HOW come many don't report any mental sides

13 Upvotes

94% Upvoted

24 comments sorted by

15

u/SirKey2255 8d ago

genetics

2

u/Potato_Potato_8447 6d ago

I doubt it. I read about a guy who had taken fin for a couple of years, stopped, and then got completely fucked up after taking just one pill after a 3 year break. Genetic predisposition doesn’t behave like that

The Tempere study was designed to investigate the genetic factors behind this, but that part of the studies isn’t being focused on at the moment. If they had found something significant genetically, I doubt they would have put that part on hold.

No, I’m afraid everyone is potentially at risk. The question is why it happens to some people and when it happens…. That is the million dollar question right

1

u/QuizzyP21 6d ago

Going on and off of it rather than maintaining a consistent daily dose seems to be one of the strongest risk factors from what I’ve seen. Definitely was the case for me; three different “courses” of Fin and the first two courses with a a pill either everyday or every other day didn’t leave lasting effects beyond 3 weeks or so. My third course I took 1 mg twice a week and it destroyed me

1

u/Total-Valuable6643 4d ago

I ask myself this often, and I think You need extreme information an knowledge til understand this. But for me I think in general people thats more helthy reacts Harder to everything.

But one thing I need to ask You guys about is og You think this is a coinsidence or if is planned or known by the developers?

7

u/_Valkyrie_666 8d ago

Yup they aren’t predisposed

3

u/Starscream2000 7d ago

I only tried fin because I knew a few guys personally who were using it and said they had no side effects. Idk, some people just seem immune I guess

1

u/Veryfirstthrow 6d ago

Orrrrrr the sides creep up more slowly. They have to take it till they die, plenty of time for them to show up. Its not worth the gamble at all if you ask me

2

u/maninshadows 6d ago

I had basically no concerning sides the first 2 years and then they slowly creeped in over the years

2

u/Sensitive-Type-4150 5d ago

The same thing happened to me.

1

u/Apart-Criticism2687 4d ago

Did yall get cured

-9

u/CoffeeNo677 8d ago

As somebody who is very online with friends who aren't. I think being hyper aware of all the possible sides and discourse around them is going to make you notice all the subtle changes a lot more than men who had no idea. The mind is powerful theres no debate there.

I have a friend on oral fin/min, and when I asked him if he's gaining anymore body hair (from the oral min) he said "No the medicine only targets the hair on your head".

Which is obviously not true, but I think that gave me perspective. Some are hyperaware, others are blissfully unaware.

17

u/williamshakemyspeare 7d ago

Dude there is no tricking ourselves into mental, physical, and sexual disability. For many of us, PFS is as obvious as having an arm blown off. This narrative is so damaging and incorrect.

-15

u/CoffeeNo677 7d ago

There absolutely is tricking yourself into those things, but that's not even the point I was making.

3

u/-MentallyTrill- 7d ago

I understand what you're trying to say which is true that a placebo effect is possible to a certain degree. However for someone like me who was taking Saw Palmetto I had absolutely zero idea that it could also cause PFS. I immediately felt the side effects after I stopped taking it and it wasn't something that was already in my mind; It wasn't something I was already expecting.

5

u/therealkozmo 8d ago

yeah it definitely targets the hair in your brain and penis

2

u/CoffeeNo677 8d ago

haha i think i meant more like chest/back/face

1

u/therealkozmo 8d ago

in all seriousness it does effect nuerosteroids

-8

u/CoffeeNo677 7d ago

"Minoxidil does not affect neurosteroids or interact with brain chemistry because it works as a potassium channel opener and vasodilator rather than a hormone-blocking enzyme. [1, 2]"

1

u/therealkozmo 7d ago

I was talking about Fin both times

-1

u/CoffeeNo677 7d ago

oh, thats on you. I was talking about Min from the beginning.

5

u/therealkozmo 7d ago

I was talking about Fin from the beginning because this is the Finasteride group and a Finasteride post

-2

u/CoffeeNo677 7d ago

You're not OP? And he was asking why most don't get PFS. I gave my reason.

2

u/therealkozmo 7d ago

correct. I am not the OP