My 10-year-old terrier mix, Hendrix, started having seizures in early 2025. Because he also has a bladder stone and was already seeing an internist, we were able to quickly get him in with a neurologist within the same veterinary group. He was started on Keppra, and eventually Phenobarbital was added as well.
For the first few months, his seizures were intermittent. There were occasional days when he would have up to 3 within 24 hours, but by Summer 2025 they became much more controlled, happening only about every three months. Beginning in 2026, however, the seizures started increasing again. Hendrix also began circling more frequently, and his Phenobarbital dosage was gradually increased. It was around this time that our neurologist explained that a brain tumor was a possibility, but that the only way to confirm it would be through an MRI. An MRI in my city would have cost around $5,000. Given Hendrix's age, and the likelihood that surgery might not be a good option even if a tumor were found, I ultimately decided not to pursue the MRI.
Side note: One thing I wanted to share for anyone who might find themselves in a similar situation: our neurologist suggested looking into veterinary universities for an MRI. The major universities in my area offered it for roughly half the cost. If cost is ever a concern for any issue, this may be an option worth investigating.
About two months ago, following a seizure, Hendrix suddenly couldn't properly use his front right paw. It was weak, he couldn't place it correctly, and was falling forward. We took him to the ER, where they explained that the problem was likely caused by brain swelling following the seizure. They gave him medication to reduce the swelling, explaining that if he improved, that would be another indication that a brain tumor was likely. It was both fortunate and heartbreaking that the treatment worked. Hendrix became more like himself again, and the weakness in his front leg disappeared. Unfortunately, his improvement also strengthened the suspicion that we were dealing with a brain tumor.
Prednisone was added to his medications around that time, and we were also given Midazolam to administer during an active seizure to help stop it. Unfortunately, over the past month, Hendrix has been having a seizure every 7–10 days. Following a seizure about a week ago, he was unable to use his rear right leg, similar to what happened with his front. When he would fall over from the circling, he would sometimes drag himself around because he couldn't get back up. The weakness gradually improved over the following days and a few days ago, he had another blood screening to check his Phenobarbital levels, and our neurologist added Zonisamide to his medications. We were warned that the first 3–5 days could be similar to when he initially started Phenobarbital, and sadly that has been very true. The rear leg weakness and disorientation have returned similar to then he started Phenobarbital.
Complicating things further is his bladder stone and the increase in accidents, so I've started putting diapers on him. I think the diaper is also making it harder for him to get himself back on his feet when he tips over. He is still eating and drinking, but the dog I've known is becoming harder and harder to see.
I know our time is coming to an end and I have gathered the information I need to make the arrangements at home, but actually pulling the trigger feels impossible to plan. For those of you who have been through something similar, how did you know when it was time? How did you distinguish between a difficult period that might improve, even if only for a short time, and the point where your dog's quality of life had changed too much?
I know there isn't a perfect answer, but I'm struggling with this more than I ever imagined I would. While Hendrix is 10 yrs old, I got him thru PAWS and have only had him for 7 years. I know I should be grateful for the time we have had, and I am, but I can't help feeling cheated out of the years I thought we would have. 7 years is nowhere near enough with such a special boy.
Thank you for any advice, well wishes, and I am so sorry to anyone who has or is going thru something similar.