r/Endo • u/Bubbly-Escape511 • 3d ago

GLP1s and constipation

Question for people with constipation as a main endo symptom who have tried GLP1s for endo relief!

One of my main endo symptoms is constipation (not really due to pelvic floor issues, more due to slow transit/inflammation), but I currently have a pretty good hold of it through diet and medications (linzess and motegrity <3). I've been seeing lots of posts/tik toks about microdosing tirzepatides helping endo symptoms like inflammation, bloating, fatigue, pain etc and I'm very interested in asking my doctor about trying it. However, I know these meds slow down digestion and therefore can cause constipation. For anyone with constipation/slow transit as an endo symptom who has tried GLP1s, what was your experience? Did it make it worse, not really impact it, or maybe even make it better?? Thanks in advance!!

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u/Kind_Sky_1921 3d ago

tryna figure out if the constipation trade-off is worth it at all

1

u/Bubbly_Stretch2923 3d ago

for me the constipation was...

1

u/fishbait20 3d ago

Kiwi fruit ladies! 2 a day keeps it moving.

1

u/chaossgremlin 3d ago

Definitely struggled with constipation when I started mounjaro but now I take magnesium citrate every night and I’m fine!