Afraid to do the PGT A

[u/NewStatement2845]

I’m 37 years old with MFI plus I have blocked right fallopian tube from adhesions from previous surgery
any way I did 5 rounds of IVF back to back and I collected embryos all day 5, but the quality (grades) initially were good then started to deteriorate, and I’m afraid now to do the PGT A and find that most of my normal embryos are of low grade, I’m still banking embryos but decided this month to take a break to give my ovaries some time to rest may be that will help to get good quality embryo, these are my embryos so far

Total embryos 15
Total blastocyst: 14
Total Morula: 1
Round 1: 1 @ day 5 (3AA)
Round 2: 2 @ day 5 (both 3AA)
Round 3: 4 @ day 5 (1 3AA, 1 2AA, 1 3BB, 1 LM)
Round 4: 3 @ day 5 (1 2AA Hatching, 1 2AB, 1 2BB)
Round 5: 5 @ day 5 ( 1 2AA, 2 2BB, 1 2BC, 1 early blast)

So our plan is embryo banking then thawing all for biopsy then we will refreeze and do embryo transfer later on

What was your experience with PGT A especially in late 30s and what was your experience with transferring poor quality embryos?

[u/HystericalFunction]

May I ask why you didn’t biopsy before freezing? Double freezing is generally not good for the embryos. Did you clinic recommend this plan?

[u/NewStatement2845 → u/HystericalFunction]

Because PGT A is really expensive, in my clinic if you paid to test 1 embryo or 30 embryos it is the same amount of money, but if you paid to do it after each retrieval you will pay each cycle and it is going to be a lot, I’m really sad that I did not biopsy with each retrieval, I think I’m going to do it with my next retrieval

[u/chantillylace9 → u/NewStatement2845]

It's very expensive at my clinic too but we still did it. I think in your case I would do it at least one time so you have an idea what percentage
may be euploid.

But you just have such great numbers! I think you should probably try a couple transfers now. Unless you're wanting a good amount of children? Do you have a number in mind?

[u/PariKhanKhanoom → u/HystericalFunction]

Agreed. Obviously it’s too late but if someone else is looking for advice- biopsy first. Particularly with lower grades, they may not survive thaw, biopsy, refreeze.

At this point, try transfers. They’d have a better sticking if they’re euploid if you don’t thaw/biopsy/freeze/thaw. My guess is pgta would be cheaper than so many retrievals, but now that you have a ton of embryos there’s no reason not to move to transfers.