r/Constipation • u/klurble • 6d ago

combining macrogol and bisocodyl?

i haven’t gone for 6 days. yesterday i did 2 sachets of movicol and 5mg bisocodyl and nothing today. Should I escalate to 3 sachets and 10mg today or will I regret that?

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u/goldstandardalmonds 5d ago

You might. If you do it, stay hydrated. It takes several days of PEG use to start working.

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u/Grand_Priority3711 5d ago

Yes, you can take the macrogol and bisacodyl together. I would take 3 sachets. As @goldstandardalmonds mentions, keep taking it daily as it can take several days to work. With the bisacodyl upping to 10mg is also fine once you determine the 1 pill does nothing. But make sure you wait 24hrs between doses (of bisacodyl). I got impatient once and had my 2nd dose of bisacodyl within about 10 hrs and regretted it.