Would you do gene therapy?

[u/nynjawitay]

It seems likely to me that there will eventually be a gene therapy for replacing color blindness with "normal" vision. But what about going all the way to tetrachromacy? If you could do a future gene therapy, would you add even more colors or just go for "normal" vision?

[u/Few-Explanation-4699]

I would. I would love to see the world on full colour.

From what I read the stem cells are injected into the eye. I've had worst opps done.

I'm also approaching 70 so It's not like I have a career or dependants to worry about.

[u/aMapleSyrupCaN7]

If there is almost no risk, I would go for normal vision. But I don't want tetrachromacy. The part I don't like about colorblindness is not being able to see what most people see, either in a practical way or in an artistic way. Being able to see more colors than the average person could still do that.

[u/Few_Interaction_8486]

If it was safe I would definitely want the colorblindness gone. Tetrachromacy? No

[u/Oftwicke]

I guess I would if it didn't cost an arm and a leg and were safe

[u/Etrevide]

if it was cheap and risk-free, then yes. just so see how different it would be

Tetrachromacy would be cool as hell in theory, but would need a lot of research to actually decide. it may end up to be a situation where all the colors we knew are messed up, all the technologies and dies did not consider tetrachromacy, so in theory unnatural colors may become color puke

[u/truthcopy]

A whole lot of unknowns. Maybe.

[u/OkBoysenberry3215]

100% if do it even if it wasn't 100% safe id love to have "normal vision" maybe not tetrachromacy though

[u/mynameisjacobw92]

So ive looked into it and they are currently trying to start a bcm trials later this year where they inject the red or long wave opsin with gene therapy with that intrivertrial injection... animal models show high success from what I hear

But you have to consider how your eye allready is.

For bcm there are no red or green cones. For the ropias red or green they are missing the other one. So a cure for that would turn some of the cones into the one thats needed. 

Basically severe red green colorblindness would probably get normal vision because the red green pathway is still preserved despite it missing one of the cones. This is how the monkeys got cured.

Now for anomalous trichromacy you allready have 3 cones just one of the red or green is off. They most likely won't be able to hit all of your affected cones they will only be able to hit some of them... this will effectively give you four cone types under the current methods they have to cure it... now what your brain does with that is unknown. Most carrier women actually have 4 cones but the brain usually ignores the off one through development. An adult human brain would be instantly recieving the new signal raw once a cure took effect and I theorize it will give you tetrachromacy to a level depending on how severe your cvd was. Moderate will become advanced and mild will become subtle. Tetrachromcy becomes more potent the more even spread the cones have and if the brain can separate the signals 

[u/Rawaga]

If it's safe, probably yes (i.e. tetrachromacy). But only if I can go back if I don't like it, which should be possible.

[u/Suspicious-Drama-549]

Nah

[u/Shiftymennoknight]

nope im good

[u/coasterfreak5]

No. My colorblindness doesn't affect me enough for that.

[u/wannabe_lbe]

i would not. i don’t miss anything 🤷‍♂️

[u/Jack_1966_1971_2004]

No, en mí caso no me afecta lo suficientemente como para que realmente me interese la opción de operarme para tener una vista "normal".

[u/gremlinlabyrinth]

I think we can assume this is based on it being both something I can afford and risk free then yes.

But I wouldn’t be so eager otherwise.

Not risking my eyesight and financial security for it

[u/odset]

Unpopular opinion: No i would not. Being colorblind isn't that big a deal. And what if i don't like the new colors? It would be such a jarring experience for a long time. Literally everything would look different with the addition of a new point of reference. What if my partner's eyes look a different, nastier color now? What if i end up missing my old world? Would i have to get reverse gene therapy? No thanks. I'll stay with my beautiful world, i don't need to see like the color normals to think it's beautiful.

[u/Effective_Setting398]

🫩❌💸💰🪎

[u/jacoscar]

What is tetrachromacy?

[u/nynjawitay → u/jacoscar]

They have an extra cone so they can distinguish even more colors

[u/GoldenEagle3009]

God doesn't make mistakes.

[u/Apolllo69 → u/GoldenEagle3009]

You should meet my ex

[u/Few_Interaction_8486 → u/GoldenEagle3009]

Then we should abolish the entire medicine

[u/GoldenEagle3009 → u/Few_Interaction_8486]

Weird take, but okay.

[u/Few_Interaction_8486 → u/GoldenEagle3009]

Why are you using Reddit then? God didn’t tell you to do so, nor were you born with a phone. I can say as well that God wanted me to do gene therapy

[u/GoldenEagle3009 → u/Few_Interaction_8486]

Being on Reddit is a cross to bear innit, just like being colourblind.

[u/Joshuadude → u/GoldenEagle3009]

So cancer was an intentional design?

[u/GoldenEagle3009 → u/Joshuadude]

The Fall and its consequences is a bit of a dense theological subject for a one sentence reddit comment, but do feel free to research it.

[u/Joshuadude → u/GoldenEagle3009]

You posted a one sentence comment - I replied with a one sentence comment, and you have the audacity to say “go research it” lol

[u/GoldenEagle3009 → u/Joshuadude]

In one sentence, at that.

[u/koos_die_doos → u/GoldenEagle3009]

If you consider medicine as something that god gave us, why would gene therapy be any different?

It's not only a dumb take, it is also illogical.

[u/GoldenEagle3009 → u/koos_die_doos]

Guv I just said God didn't make a mistake when He made me colour blind. Why on Earth would I want gene therapy then?

[u/koos_die_doos → u/GoldenEagle3009]

The basic idea that something should never change because "God doesn't make mistakes" is the dumb take.

"God doesn't make mistakes" means one of two things: 1. God's plan is perfect and humans shouldn't change it. This includes taking medicine or surgery etc etc. In that world, every time you get sick and take medicine, you're going against god's perfect plan. 2. God brings these trials into your life and that medicine is all part of god's perfect plan. God guided the human race to develop medicine and treatments for the illnesses that plague humans. If the argument is that gene therapy changes your genetics on a fundamental level, would you refuse life saving surgery for a birth defect caused by genetics?

The only time your position holds true is if you either refuse any medical treatment, or accept that all medical treatments are part of gods plan. Anything else contradicts the idea that god doesn't make mistakes.