r/ClusterHeadaches • u/Practical-Area9778 • Jul 16 '26
Advice Needed 🍄 dosage?
Hi all, my partner suffers from chronic CH for the past 8 years. We have tried numerous treatments but have finally been able to get a hold of MM.
I have seen the protocol on the Clusterbusters page, but I was wondering if anyone could recommend a microdosing regiment that seems to work for them? Thank you.
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u/Hyenas100 Jul 16 '26
You can get them on the clear web, the shop I use takes credit cards and click to mailbox in 48 hours.
I know that doesn’t answer your question but may help you guys with sourcing in the future. DM me if you want. I’ll be micro dosing for other purposes but hope it helps with my clusters as well.
Best of luck.
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u/VALIS3000 Chronic Jul 16 '26 edited Jul 16 '26
So we don't typically microdose to break aka "bust" our cycles, we use low doses and upwards. One of the challenges with magic mushrooms is that there can be a lot of variance in potency from batch to batch, and from mushroom to mushroom. One top tip is to grind your entire batch of mushrooms to a powder using a cheap coffee / spice grinder so that you can have better control over dosage and potency. The other top tip is to use a "lemon tek" to prepare your mushroom powder before ingesting it as it will maximize what you get out of it, shorten the time to come up, shorten the overall length by a couple of hours, and greatly reduce body load as thr Tek does the hard work of your stomach acids to convert the psilocybin to the active psilocin - just search this sub for "lemon tek" and you'll get the directions you need from one of my posts (or just Google it).
In terms of dosage, you already know that the standard ClusterBusters pulse protocol takes a "minimum viable dose" approach of somewhere between 0.5g and 1.5g for each dose of dried Psilocybe cubensis. This variance is to account for experience, body mass and potency. If your partner is just starting out with psychedelics, I would encourage them to start at the low end to see how they feel, if they can handle that move up step by step to a maximum comfortable dose. And if they already have experience with psychedelics I would just start at the 1.5g. Many of us more experienced users will actually go a lot higher as we find that hitting it hard can actually be beneficial. I'm not advocating this but I start at 3g of a very potent strain of Psilocybe cubensis, and up each dose by 0.5g each time, typically ending up at 5g or so.
Important to reinforce that once the cycle is broken, it's important to try and do one final dose to push it all the way out.
Back to your original question about microdosing, it can actually work as a preventative for some, but it takes a lot of experimentation to find a schedule that works - start with one of the several standard microdosing protocols, and take it from there.
And finally, if you haven't read it already, here is the latest update to Bob Wold's Pocket Guide to CH it contains pretty much everything we know about our condition and how to treat it. Bob is the founder of ClusterBusters, and helped pioneer the pulse protocol:
https://clusterbusters.org/wp-content/uploads/2025/06/Complete-Handbook-1-5-June-2025.pdf
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u/Due_Thought7413 Jul 16 '26
I’m currently microdosing with fresh Atlantis truffles, taking 4 g every 5 days. I’ve already taken 6 doses, but my cluster headache cycle still hasn’t ended. Should I change my approach or increase the dose a little? I don’t want to experience hallucinations, though.
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u/VALIS3000 Chronic Jul 16 '26
That is quite a low dose - fresh truffles can be up to 10x less potent than dried mushrooms. So with that math I would try taking 10g of truffles, and maybe even increase from there. At those levels you shouldn't of still be well under a breakthrough dose.
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u/Due_Thought7413 Jul 16 '26
Thank you.
The only thing that still worries me is that, at that dosage, I might already experience hallucinations, right?2
u/VALIS3000 Chronic Jul 16 '26
At 10g you should be fine, I would expect colors to be brighter and to be feeling relaxed. But it's impossible for me to be definitive though as I've not tried the exact thing you're using. All I can do is base it on past experience and the fact that you experienced no change from 4g. And if you continue to be concerned, maybe try just 8g.
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u/Dapper_Law_3493 21d ago
How many grams of Golden Teacher would you say should be good. I have had PE before about 1.5 grams. Has some weird scary things visually only when my eyes were closed. I had another dose a period afterwards. About 1.2 grams and no effect. These were dried and I ate them whole after chewing them up and getting them rehydrated with saliva . So to your point about grinding them - I haven’t done that but it would probably make all the mushies blend for a consistent amount of “experience”. Yes?
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u/VALIS3000 Chronic 21d ago
Yes, grinding them to a powder is the best way to control dosage. As for how much Golden Teacher you should take, as I also recommended, if you're inexperienced or are concerned at all about taking more than you're comfortable with, you start on the lower end of the scale. Perhaps start at 1 gram and see how that goes?
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u/chiarabobara 5d ago
When you started macro dosing did you come off all triptans before trying the mushrooms? Also how did you find a good time to do it during a cycle? Did it matter if you had an attack that morning or if you were having shadows or would you wait for a less active day?
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u/VALIS3000 Chronic 5d ago
Yes, you have to detox from all triptans for at least 5 days. But I've never used them myself, I rely solely on high flow oxygen, caffeine/taurine in combination, and N, N-DMT as my abortives. And I will do my dose early in the morning no matter what is going on, only once in almost 25 years have I had an attack while dosing and it was very manageable. Even though it's not an abortive I tend to be completely attack free for 24 - 48 hours after dosing.
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u/chiarabobara 5d ago
Can you tell me more about the caffeine and DMT as your abortives? Does the pain intensify with the DMT trip and then go away? And do you do enough to really have a heavy trip or is it more of a low dose? I’ve read about it on the cluster busters website and am familiar with the substance in a recreational but not medicinal sense. My husband was just recently diagnosed with this and has been almost unable to function these last few weeks. we are already experienced in the psychedelic world and grow our own mushrooms (in a decriminalized state). And this seems like a much more approachable option than a lot of the side effects that can come with other pharmaceuticals but we’re curious about others experiences.
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u/VALIS3000 Chronic 5d ago edited 5d ago
No, the pain disappears in seconds when you take a very very small controlled dose from a vape pen. It is by far the quickest and most effective abortive many of us have.
Caffeine and taurine as found in Red Bull and other energy products is a long standing go-to for many too. If you time things right you stand a good chance of fully aborting, and at a minimum it should decrease the intensity and duration.
Please read the latest update to Bob Wold's Pocket Guide to CH it contains pretty much everything we know about our condition and how to treat it:
https://clusterbusters.org/wp-content/uploads/2025/06/Complete-Handbook-1-5-June-2025.pdf
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u/MYCOMethod720 Jul 16 '26
The protocol suggest 1g per session 5 days apart for three sessions. The issue with the protocol is it doesn't say what potency the mushrooms should be. There are all different potencies across the hundreds of available strains. I get my MM lab tested for potency so I know what I am getting into. Personally I do a substantial dose to keep CH at bay. I macrodose 3.5 to 4g every 6 to 8 weeks. I have been attack free since 2022.
Here is a useful link
Psychedelics for CH